| clinical trials, phase II | Studies that are usually controlled to assess the effectiveness and dosage (if appropriate) of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques. These studies are performed on several hundred volunteers, including a limited number of patients with the target disease or disorder, and last about two years. This concept includes phase II studies conducted in both the u.s. And in other countries. (12 Dec 1998) |
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| clinical trials, phase III | Comparative studies to verify the effectiveness of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques determined in phase II studies. During these trials, patients are monitored closely by physicians to identify any adverse reactions from long-term use. These studies are performed on groups of patients large enough to identify clinically significant responses and usually last about three years. This concept includes phase III studies conducted in both the u.s. And in other countries. (12 Dec 1998) |
| clinical trials, phase IV | Planned post-marketing studies of diagnostic, therapeutic, or prophylactic drugs, devices, or techniques that have been approved for general sale. These studies are often conducted to obtain additional data about the safety and efficacy of a product. This concept includes phase IV studies conducted in both the u.s. And in other countries. (12 Dec 1998) |
| clinician | A health professional engaged in the care of patients, as distinguished from one working in other areas. (05 Mar 2000) |
| clinicopathologic | Pertaining to the signs and symptoms manifested by a patient, and also the results of laboratory studies, as they relate to the findings in the gross and histologic examination of tissue by means of biopsy or autopsy, or both. (05 Mar 2000) |
| clino- | A slope (inclination or declination) or bend. Origin: G. Klino, to slope, incline, or bend (05 Mar 2000) |
| clinocephalic | Clinocephalous Relating to clinocephaly. (05 Mar 2000) |
| clinocephaly | Craniosynostosis in which the upper surface of the skull is concave, presenting a saddle-shaped appearance in profile. Synonym: saddle head. Origin: clino-+ G. Kephale, head (05 Mar 2000) |
| clinodactyly | Permanent deflection of one or more fingers. Origin: clino-+ G. Daktylos, finger (05 Mar 2000) |
| clinography | Graphic representation of the signs and symptoms exhibited by a patient. Origin: G. Kline, bed, + grapho, to write (05 Mar 2000) |
| clinoid | 1. Resembling a four-poster bed. Synonym: clinoid process. Origin: G. Kline, bed, + eidos, resemblance (05 Mar 2000) |
| clinoid process | One of three pairs of bony projections from the sphenoid bone: anterior clinoid process, the recurved posterior angle of the lesser wing; middle clinoid process, a little spur of bone on the body of the sphenoid, posterolateral to the tuberculum sellae; posterior clinoid process, a spur of bone at each superior angle of the dorsum sellae. Synonym: processus clinoideus, clinoid. (05 Mar 2000) |
| clinoscope | <instrument> An obsolete instrument for measuring cyclophoria. Origin: clino-+ G. Skopeo, to view (05 Mar 2000) |
| clioquinol | <chemical> A potentially neurotoxic 8-hydroxyquinoline derivative long used as a topical anti-infective, intestinal antiamebic, and vaginal trichomonacide. The oral preparation has been shown to cause subacute myelo-optic neuropathy and has been banned worldwide. Pharmacological action: amebicides, anti-infective agents, local. Chemical name: 8-Quinolinol, 5-chloro-7-iodo- (12 Dec 1998) |
| clioxanide | 4'-Chloro-3,5-diiodosalicylanilide acetate;an anthelmintic. (05 Mar 2000) |