| ARNMD | Association for Research in Nervous and Mental Diseases |
|---|---|
| CBER | Center for Biologic Evaluation and Research |
| CDER | Center for Drug Evaluation and Research; chronic granulomatous disease |
| CIREN | Crash Injury Research and Engineering Network |
| CPRD | Committee on Prosthetics Research and Development |
| carboxyl and carbamoyl transferases | <enzyme> A group of enzymes that catalyze the transfer of carboxyl- or carbamoyl- groups. Registry number: EC 2.1.3 (12 Dec 1998) |
|---|---|
| Gaddum and Schild test | A sensitive method for identification of epinephrine in tissue or other material, based on the fluorescence of epinephrine exposed to ultraviolet light in the presence of alkali and oxygen; sensitivity ranges from 1:50 to 1:100 million. (05 Mar 2000) |
| vaginal creams, foams and jellies | Medicated dosage forms for topical application in the vagina. A cream is a semisolid emulsion containing suspended or dissolved medication; a foam is a dispersion of a gas in a medicated liquid resulting in a light, frothy mass; a jelly is a colloidal semisolid mass of a water soluble medicated material, usually translucent. The concept includes vaginal creams, foams, and jellies in general or for which there is no other specific heading. (12 Dec 1998) |
| magnesia and alumina oral suspension | A mixture of magnesium hydroxide and variable amounts of aluminum oxide; used as an antacid. (05 Mar 2000) |
| maintenance and engineering, hospital | Hospital department whose primary function is the upkeep and supervision of the buildings and grounds and the maintenance of hospital physical plant and equipment which requires engineering expertise. (12 Dec 1998) |
| P and P test | A test formerly used by some to control anticoagulant therapy with bishydroxycoumarin and indandione drugs. Synonym: P and P test. (05 Mar 2000) |
| malignancy and immunodeficiency | <radiology> High risk of malignancy (especially lymphoma/leukaemia, GI tumours): X-linked agammaglobulinaemia (Bruton's), common variable immunodeficiency, severe combined immunodeficiency (SCID kids), ataxia-telangectasia, Wiscott-Aldrich syndrome, selective IgA deficiency (12 Dec 1998) |
| Papillon-Leage and Psaume syndrome | <syndrome> An inherited syndrome, lethal in males, with varying combinations of defects of the oral cavity, face, and hands, including lobulated or bifid tongue, cleft or pseudocleft palate, tongue tumours, missing or malpositioned teeth, hypoplastic nasal alar cartilage, depressed nasal bridge, brachydactyly, clinodactyly, incomplete syndactyly, and, frequently, mental retardation. There are two subtypes recognised. Type I (papillon-leage and psaume syndrome, gorlin-psaume syndrome) is inherited as an x-linked dominant trait and is found only in females and XXY males. Type II (mohr syndrome) is inherited as an autosomal recessive trait. Inheritance: autosomal recessive and X-linked. Synonym: OFD syndrome, orofaciodigital syndrome, Papillon-Leage and Psaume syndrome. (05 Mar 2000) |
| Gell and Coombs Classification | A classification system that differentiates the 4 types of hypersensitivity reactions: Type I: anaphylactic reactions, Type II: cytotoxic reactions, Type III: immune complex reactions, and Type IV: cell-mediated reactions. (05 Mar 2000) |
| rate setting and review | A method of examining and setting levels of payments. (12 Dec 1998) |
| ratio of decayed and filled surfaces | An index of decayed and filled permanent surfaces per person, per full complement of 122 tooth surfaces. (05 Mar 2000) |
| ratio of decayed and filled teeth | An index of decayed and filled permanent teeth per person, per full complement of 28 teeth. (05 Mar 2000) |
| receptors, cytoplasmic and nuclear | Proteins in the cytoplasm or nucleus that specifically bind signalling molecules and trigger changes which influence the behaviour of cells. The major groups are the steroid hormone receptors, which usually are found in the cytoplasm, and the thyroid hormone receptors, which usually are found in the nucleus. Receptors, unlike enzymes, generally do not catalyze chemical changes in their ligands. (12 Dec 1998) |
| maternal age 35 and over | Pregnancy in women 35 or more years of age. It is used for normal pregnancies and for problems of pregnancy occurring in a woman's late reproductive years. These include effects on the mother's physical and mental health as well as risks of perinatal mortality and foetal abnormality. (12 Dec 1998) |
| VH and VL genes/domains | VH and VL genes define in part the sequences of the variable heavy and light regions of immunoglobulin molecules. VH and VL domains are the regions of amino acid sequence so defined. J genes and, in the case of the heavy chain, a D gene (D=diversity) also define these regions. Gene rearrangement also plays a role in determining the sequences in which the genes are joined as the DNA of the immunoglobulin producing cell matures. (18 Nov 1997) |