| OCA | oculocutaneous albinism; olivopontocerebellar atrophy; oral contraceptive agent |
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| OPCA | olivopontocerebellar atrophy |
| PMA | index of prevalence and severity of gingivitis, where P = papillary gingiva, M = marginal gingiva, a... |
| POA | pancreatic oncofetal antigen; phalangeal osteoarthritis; preoptic area; primary optic atrophy |
| PPCRA | pigmented paravenous chorioretinal atrophy |
| facioscapulohumeral atrophy | A relatively benign type of muscular dystrophy commencing in childhood and slowly progressive; characterised by wasting and weakness, sometimes asymmetrical, mainly of the muscles of the face, shoulder girdle, and arms; autosomal dominant inheritance. Synonym: facioscapulohumeral atrophy, Landouzy-Dejerine dystrophy. (05 Mar 2000) |
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| yellow atrophy of the liver | See: acute yellow atrophy of the liver. (05 Mar 2000) |
| familial spinal muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| Kienbock's atrophy | Acute atrophy of bone in an extremity following inflammation. (05 Mar 2000) |
| fatty atrophy | Fatty infiltration secondary to an atrophy of the essential elements of an organ or tissue. (05 Mar 2000) |
| Zimmerlin's atrophy | A variety of hereditary progressive muscular atrophy in which the atrophy begins in the upper half of the body. (05 Mar 2000) |
| Leber's hereditary optic atrophy | Hereditary degeneration of the optic nerve and papillomacular bundle with resulting rapid loss of central vision, progressive for several weeks, then usually stationary with permanent central scotoma; age of onset is variable, most often in the third decade; more males than females are affected and transmission is cytoplasmic and strictly on the female side. Mutation on the mitochondrial chromosome involved, which presumably interacts with an X-linked mutant. This mechanism may explain the bizarre sex ratio, which differs significantly from one country to another. (05 Mar 2000) |
| linear atrophy | Bands of thin wrinkled skin, initially red but becoming purple and white, which occur commonly on the abdomen, buttocks, and thighs at puberty and/or during and following pregnancy, and result from atrophy of the dermis and overextension of the skin; also associated with ascites and Cushing's syndrome. Synonym: atrophoderma striatum, lineae albicantes, lineae atrophicae, linear atrophy, stretch marks, stria, striae atrophicae, striate atrophy of skin, traction atrophy, vergeture. (05 Mar 2000) |
| accessory thyroid | An isolated mass, or one of several such masses, of thyroid tissue, sometimes present in the side of the neck, or just above the hyoid bone (suprahyoid accessory thyroid gland), or even as low as the arch of the aorta. Synonym: glandula thyroidea accessoria, accessory thyroid, prehyoid gland, suprahyoid gland, thyroidea accessoria, thyroidea ima, Wolfler's gland. (05 Mar 2000) |
| accessory thyroid gland | An isolated mass, or one of several such masses, of thyroid tissue, sometimes present in the side of the neck, or just above the hyoid bone (suprahyoid accessory thyroid gland), or even as low as the arch of the aorta. Synonym: glandula thyroidea accessoria, accessory thyroid, prehyoid gland, suprahyoid gland, thyroidea accessoria, thyroidea ima, Wolfler's gland. (05 Mar 2000) |
| anaplastic carcinoma of the thyroid | <oncology, tumour> An aggressive form and rare form of thyroid cancer that is one of the most rapidly growing and invasive types of thyroid cancer. It commonly occurs in people over 60 years of age and may cause obstruction of the trachea. The cause is unknown but exposure to radiation may be a factor. Thyroid function tests are usually normal. Hoarse voice, cough and coughing up blood are common symptoms. Examination may reveal nodules in the thyroid gland. Diagnosis is made via biopsy. Treatment is surgical with or without radiation therapy. (27 Sep 1997) |
| cancer, thyroid | Cancer of the gland in front of the neck that normally produces thyroid hormone which is important to the normal regulation of the metabolism of the body. There are four major types of cancer of the thyroid gland. Persons who received radiation to the head or neck in childhood should be examined by a doctor every 1 to 2 years. The most common symptom of thyroid cancer is a lump, or nodule, that can be felt in the neck. The only certain way to tell whether a thyroid lump is cancer is by examining the thyroid tissue obtained using a needle or surgery for biopsy. (12 Dec 1998) |
| receptors, thyroid hormone | Proteins, usually found in the nucleus, that specifically bind thyroid hormones and regulate DNA transcription. These proteins, termed c-erba, are activated by hormones and cause differentiation of erythroid progenitor cells which irreversibly lose proliferative potential. Thus c-erba proteins act as growth suppressors. The c-erba proteins are encoded by at least two genes, c-erba alpha and c-erba beta. Each of these has two isoforms. Mutations in the ligand-binding domain of the beta form causes thyroid hormone resistance syndrome. (12 Dec 1998) |
| giant cell carcinoma of thyroid gland | A rapidly progressive undifferentiated carcinoma observed in the thyroid gland, characterised by numerous, unusually large, anaplastic cells derived from glandular epithelium of the thyroid gland. (05 Mar 2000) |
| glandular branches of inferior thyroid artery | <anatomy, artery> Branches of inferior thyroid artery to thyroid and parathyroid glands, anastomosing with branches of superior thyroid artery. Synonym: rami glandulares arteriae thyroideae inferioris. (05 Mar 2000) |