| AIA | allylisopropylacetamide; amylase inhibitor activity; anti-immunoglobulin antibody; anti-insulin anti... |
|---|---|
| ANA | acetylneuraminic acid; American Narcolepsy Association; American Neurological Association; American ... |
| APA | action potential amplitude; aldosterone-producing adenoma; Ambulatory Pediatric Association; America... |
| ATA | alimentary toxic aleukia; American Thyroid Association; aminotriazole; antithymic activity; antithyr... |
| EA | early antigen; educational age; egg albumin; electric affinity; electrical activity; electroacupunct... |
| T enzyme | 1,4-alpha-d-glucan 6-alpha-d-glucosyltransferase. (05 Mar 2000) |
|---|---|
| terminal addition enzyme | <enzyme> A non-template-directed DNA polymerase normally found in vertebrate thymus and bone marrow. It catalyses the elongation of oligo- or polydeoxynucleotide chains and is widely used as a tool in the differential diagnosis of acute leukaemias in man. Chemical name: Nucleoside-triphosphate:DNA deoxynucleotidylexotransferase Registry number: EC 2.7.7.31 (12 Dec 1998) |
| thermostable enzyme | <enzyme> An enzyme that is not readily subject to destruction or alteration by heat. Synonym: heat-stable enzyme. (05 Mar 2000) |
| thiol enzyme | <enzyme> An enzyme whose activity depends on a free thiol group. (05 Mar 2000) |
| ecori restriction enzyme | <enzyme, molecular biology> A commonly-used restriction enzyme (enzyme which will cleave the phosphodiester bonds of DNA at specific nucleotide sequences) that came from the bacteria Escherichia coli and recognises the sequence GAATTC. The enzyme will make a staggered cut of the double-stranded DNA molecule by cutting between the G and A on both strands. (09 Oct 1997) |
| enzyme | <biochemistry> A protein molecule produced by living organisms that catalyses chemical reactions of other substances without itself being destroyed or altered upon completion of the reactions. Enzymes are classified according to the recommendations of the Nomenclature Committee of the International Union of Biochemistry. Each enzyme is assigned a recommended name and an Enzyme Commission (EC) number. They are divided into six main groups, oxidoreductases, transferases, hydrolases, lyases, isomerases and ligases. (09 Oct 1997) |
| enzyme activation | Conversion of an inactive form of an enzyme to one possessing metabolic activity. It includes 1) activation by ions (activators); 2) activation by cofactors (coenzymes); and 3) conversion of an enzyme precursor (proenzyme or zymogen) to an active enzyme. (12 Dec 1998) |
| enzyme analog | A synthetic macromolecule having enzymatic activity. Synonym: enzyme analog. (05 Mar 2000) |
| enzyme antagonist | An antimetabolite or inhibitor of enzyme action. (05 Mar 2000) |
| enzyme-catalyzed ligation | <enzyme> An enzyme-mediated joining of phosphodiester linkage of two stretches of DNA or RNA, or of peptide linkage of two polypeptides. (05 Mar 2000) |
| enzyme defect | A disorder resulting from a deficiency (or functional abnormality) of an enzyme. In 1902 Archibald Garrod first attributed a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as PKU (phenylketonuria) and galactosaemia, an error in the handling (metabolism) of the sugar galactose. (12 Dec 1998) |
| enzyme derepression | Removing or turning off the inhibitor or inhibitors (molecules which repress or prevent other molecules from acting) enzyme so that enzyme activity can resume. (09 Oct 1997) |
| enzyme electrode | A type of biosensor. An enzyme is immobilised on the surface of an electrode, and when the enzyme catalyses its reaction, electrons are transferred from the reactant to the electrode, and a current is generated, which can then be measured. (14 Nov 1997) |
| enzyme immobilisation | The attachment of an enzyme to a solid matrix so that it cannot escape but can still act on its substrate. (09 Oct 1997) |
| enzyme immunoassay | The general term for an expanding technical arsenal of testing which allows a full range of quantitative analyses for both antigen and antibodies. These tests use colour-changed products of enzyme-substrate interaction (or inhibition) to measure the antigen-antibody reaction. Examples of EIA procedures (EMIT, ELISA, MAC, MEIA) follow. Acronym: EIA (05 Mar 2000) |