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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 6
  • Apoptosis Inducing Factor - »õâ A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.
    Synonyms : AIF Apoptosis Regulatory Protein, Apoptosis-Inducing Factor, Mitochondrial Apoptosis-Inducing Factor, Apoptosis-Inducing Factor, Mitochondrial, Mitochondrial Apoptosis Inducing Factor
  • Apoptosis Regulatory Proteins - »õâ A large group of proteins that control APOPTOSIS. This family of proteins includes many ONCOGENE PROTEINS as well as a wide variety of classes of INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS such as CASPASES.
    Synonyms : Apoptosis Inducing Proteins, Apoptosis Inhibiting Proteins, Death Factors (Apoptosis), Programmed Cell Death Proteins, Survival Factors (Apoptosis), Regulatory Proteins, Apoptosis
  • Apoptosomes - »õâ Multimeric protein complexes formed in the CYTOSOL that play a role in the activation of APOPTOSIS. They can occur when MITOCHONDRIA become damaged due to cell stress and release CYTOCHROME C. Cytosolic cytochrome C associates with APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 to form the apoptosomal protein complex. The apoptosome signals apoptosis by binding to and activating specific INITIATOR CASPASES such as CASPASE 9.
    Synonyms : Apoptosomal Protein Complex, Apoptosome, Complex, Apoptosomal Protein, Protein Complex, Apoptosomal
  • Apoptotic Protease-Activating Factor 1 - »õâ A CARD signaling adaptor protein that plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY). It binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX and activates INITIATOR CASPASES such as CASPASE 9.
    Synonyms : Apaf-1 Protease-Activating Factor, Apaf 1 Protease Activating Factor, Apoptotic Protease Activating Factor 1, Protease-Activating Factor, Apaf-1
  • Aporphines - »õâ Dibenzoquinolines derived in plants from (S)-reticuline (BENZYLISOQUINOLINES).
    Synonyms :
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 6
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