| alkylacetylglycerophosphatase | <enzyme> Involved in the synthesis of platelet-activating factor Registry number: EC 3.1.3.59 Synonym: alkylacetyl-gp phosphohydrolase, 1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase (26 Jun 1999) |
|---|---|
| alkylamine | An alkane containing an -NH2 group in place of one H atom; e.g., ethylamine. (05 Mar 2000) |
| alkylating agent | <oncology, pharmacology> A reagent that places an alkyl group, for example propyl in place of a nucleophilic group in a molecule. Alkylating reagents include a number of cytotoxic drugs some of which react fairly specifically with N7 of the purine ring and lead to depurination of DNA, for example the agent ethyl ethanesulphonic acid and thus to mutagenesis. The drugs interaction with DNAand prevents the division of the cells. Examples of drugs include: busulphan, chlorambucil, cyclophosphamide, melphalan. (29 Sep 1997) |
| alkylating agents | Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agent, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases. (12 Dec 1998) |
| alkylation | The substitution of an alkyl group for an active hydrogen atom in an organic compound. (12 Dec 1998) |
| alkyldihydroxyacetone phosphate acyltransferase | <enzyme> Catalyses acylation of alkyl-dhap Registry number: EC 2.3.1.- Synonym: adapat (26 Jun 1999) |
| alkylglycerol kinase | <enzyme> Forms 1-alkyl-2-lyso-sn-glycero-3-phosphate Registry number: EC 2.7.1.93 Synonym: alkylglycerol phosphotransferase (26 Jun 1999) |
| alkylglycerone-phosphate synthase | <enzyme> Replaces the acyl moiety of acyldhap with a long chain fatty alcohol; intact alcohol including the oxygen atom is incorporated into alkyl-dhap Registry number: EC 2.5.1.26 Synonym: adhps, alkyl-dihydroxyacetone phosphate synthase, alkyl-dhap synthase, alkyldihydroxyacetone phosphate synthetase, acylglycerone-3-phosphate-long chain-alcohol o-3-phospho-2-oxopropanyl transferase, alkyldihydroxyacetonephosphate synthase (26 Jun 1999) |
| alkylglycerophosphoethanolamine phosphodiesterase | <enzyme> From microsomal preparations of rabbit kidney medulla; hydrolyzes choline moiety from lyso-paf to form 1-alkyl-2-lysoglycerophosphate in rat brain and other tissue; only lysoglycerophospholipids with ether linkages at the sn-1 position serve as substrates; acyl analogs are not utilised; requires magnesium Registry number: EC 3.1.4.39 Synonym: lysophospholipase d (26 Jun 1999) |
| alkylhalidase | <enzyme> Acts on haloalkanes to form aldehyde and halogen(s) Registry number: EC 3.8.1.1 Synonym: haloalkane dehalogenase, 1-chlorohexane halidohydrolase, lina-like gene product, dhaa gene product (26 Jun 1999) |
| alkylmercury compounds | Organic mercury compounds in which the mercury is attached to an alkyl group. (12 Dec 1998) |
| alkylmercury lyase | <enzyme> From bacteria; catalyses the protonolysis of the carbon-mercury bond to give hydrocarbon and mercury as a mercaptide Registry number: EC 4.99.1.2 Synonym: organomercury lyase, organomercurial lyase, phenylmercury lyase (26 Jun 1999) |
| alkylsulfatase | <enzyme> Induced by sodium hexan-1-yl sulfate Registry number: EC 3.1.6.- Synonym: alkylsulfohydrolase, alkylsulphohydrolase (26 Jun 1999) |
| alkyne | <chemistry> An organic molecule containing carbon and hydrogen atoms in straight or branched chains, where at least one carbon-carbon bond is a triple bond. One of three major classes of aliphatic hydrocarbons. (13 Nov 1997) |
| alkynes | Acyclic hydrocarbons with one triple bond of the general formula cn-h2n-2. (12 Dec 1998) |