| adrenocorticotropic hormone | The hormone of the anterior lobe of the hypophysis which governs the nutrition and growth of the adrenal cortex, stimulates it to functional activity, and also possesses extraadrenal adipokinetic activity; it is a polypeptide containing 39 amino acids, but exact structure varies from one species to another; sometimes prefixed by a to distinguish it from beta-corticotropin. The first thirteen amino acids at the N-terminal region are identical to alpha-melanotropin. Synonym: adrenocorticotropin, adrenotropic hormone, adrenotropin, corticotropic hormone, corticotropin. (05 Mar 2000) |
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| adrenocorticotropic releasing factor | Hormone produced by hypothalamus that causes pituitary to secrete adrenocorticotropic hormone. (05 Mar 2000) |
| adrenocorticotropin | The hormone of the anterior lobe of the hypophysis which governs the nutrition and growth of the adrenal cortex, stimulates it to functional activity, and also possesses extraadrenal adipokinetic activity; it is a polypeptide containing 39 amino acids, but exact structure varies from one species to another; sometimes prefixed by a to distinguish it from beta-corticotropin. The first thirteen amino acids at the N-terminal region are identical to alpha-melanotropin. Synonym: adrenocorticotropin, adrenotropic hormone, adrenotropin, corticotropic hormone, corticotropin. (05 Mar 2000) |
| adrenodoxin | <chemical> An iron-sulfur protein which serves as an electron carrier in enzymatic steroid hydroxylation reactions in adrenal cortex mitochondria. The electron transport system which catalyses this reaction consists of adrenodoxin reductase, NADP, adrenodoxin, and cytochrome p-450. Chemical name: Adrenodoxins (12 Dec 1998) |
| adrenogenic | Of adrenal origin. Origin: adreno-+ G. -gen, producing (05 Mar 2000) |
| adrenogenital syndrome | <syndrome> A general term for a group of disorders which involve hyperplasia (or malignant tumours) of the adrenal cortex. Features include masculinisation of women, feminisation of men or precocious sexual development of children. (27 Sep 1997) |
| adrenogenous | Of adrenal origin. Origin: adreno-+ G. -gen, producing (05 Mar 2000) |
| adrenoleukodystrophy | <radiology> X-linked recessive, demyelination of cerebral white matter, adrenal insufficiency (unresponsive to ACTH), CT: white-matter disease: occipital regions to frontal, progression to generalised atrophy, NM: increased uptake in involved regions, ** dysmyelinating disease, white-matter disease (12 Dec 1998) |
| adrenolytic | <pharmacology> Inhibiting the action of adrenergic nerves, inhibiting the response to adrenaline. Origin: Gr. Lysis = dissolution (06 Oct 1997) |
| adrenomedullary hormones | Hormones produced by the adrenal medulla, particularly the catecholamines epinephrine and norepinephrine. (05 Mar 2000) |
| adrenomegaly | Enlargement of the adrenal glands. Origin: adreno-+ G. Megas, big (05 Mar 2000) |
| adrenomimetic | Having an action similar to that of the compounds epinephrine and norepinephrine, which are liberated from the adrenal medulla and adrenergic nerves; term proposed to replace the less accurate term, sympathomimetic. Compare: adrenergic, cholinomimetic. Origin: adreno-+ G. Mimetikos, imitative (05 Mar 2000) |
| adrenomimetic amine | An agent that evokes responses similar to those produced by adrenergic nerve activity (e.g., epinephrine, ephedrine, isoproterenol). Synonym: adrenergic amine, adrenomimetic amine, sympathetic amine. (05 Mar 2000) |
| adrenomyeloneuropathy | A disorder of adult males, consisting of long standing adrenal insufficiency, hypogonadism, progressive myelopathy, peripheral neuropathy, and sphincter disturbances; considered a variant of adrenoleukodystrophy. Origin: adreno-+ G. Myelos, medulla, + neuron, nerve, + pathos, suffering (05 Mar 2000) |
| adrenopathy | Any pathologic condition of the adrenal glands. Synonym: adrenopathy. Origin: adrenal + G. Pathos, suffering (05 Mar 2000) |