| 5-formyltetrahydrofolate cyclo-ligase |
[EC 6.3.3.2] an enzyme of the ligase class that catalyzes the ATP-dependent formation of 5,10-methenyltetrahydrofolate from 5-formyltetrahydrofolate (folinic acid). The reaction provides a means of utilization of folinic acid in the absence of dihydrofolate reductase activity. Called also 5,10-methenyltetrahydrofolate synthetase.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| 5-hydroxyindoleacetic acid |
a product of serotonin metabolism excreted in large amounts by patients with carcinoid tumors. Abbreviated 5-HIAA.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| 5-l. |
arachidonate 5-lipoxygenase.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| 5-methyltetrahydrofolate |
a substituted, reduced derivative of folic acid, occurring as a source of methyl groups for the regeneration of methionine; it is formed by reduction of 5,10-methylenetetrahydrofolate and is the principal form of folic acid during transport and storage in the body.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| 5-methyltetrahydrofolate–homocysteine S |
[EC 2.1.1.13] an enzyme of the oxidoreductase class that catalyzes the remethylation of homocysteine to form methionine, using 5-methyltetrahydrofolate as a methyl donor and requiring methylcobalamin as a coenzyme; the reaction also regenerates tetrahydrofolate. Deficiency of enzyme activity can result from any of several defects, including deficiency of the apoenzyme, inability to convert cobalamin specifically to methylcobalamin or, more generally, to either of the cobalamin-containing coenzymes, deficiency of 5,10-methylenetetrahydrofolate reductase activity, familial megaloblastic anemia or other defect in absorption or transport of vitamin B12, or nutritional deficiency of vitamin B12 or folate; it results in homocystinuria, with developmental delay and neurologic abnormalities, and hypomethioninemia. Defects in cobalamin metabolism are characterized additionally by hematologic abnormalities and some also by methylmalonicacidemia (q.v.).
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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