| 3-ketoacyl-CoA thiolase | <enzyme> An enzyme catalyzing the thioclastic cleavage by coenzyme A of beta-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation. See: acetyl-CoA acetyltransferase. Synonym: 3-ketoacyl-CoA thiolase, beta-ketothiolase. (05 Mar 2000) |
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| 3-ketodihydrosphingosine synthetase | <enzyme> Serine and palmitoyl-CoA yields 3-ketodihydrosphingosine and co2 Registry number: EC 4.1.3.- (26 Jun 1999) |
| 3-ketosphinganine reductase | <enzyme> Reduces 3-ketosphinganine to d-erythro-sphinganine in the pathway of the enzymatic synthesis of sphingolipid long-chain bases in saccharomyces cerevisiae; NADPH dependent Registry number: EC 1.1.1.- (26 Jun 1999) |
| 3-ketosphinganine synthetase | <enzyme> Palmitoyl-CoA and serine gives 3-ketosphinganine, carbon dioxide and CoA; a pyridoxal phosphate enzyme; uses ATP Registry number: EC 6.4.- Synonym: 3-ketosphinganine synthase (26 Jun 1999) |
| 3-ketosteroid reductase | <enzyme> Converts 3-keto-4-methyl steroid intermediate of cholesterol biosynthesis to 3-oh; NADPH-dependent Registry number: EC 1.1.1.- (26 Jun 1999) |
| 3-ketovalidoxylamine A C-N lyase | <enzyme> From flavobacterium saccharophilum; separates the two rings of 3-ketovalidoxylamine a Registry number: EC 4.3.3.1 (26 Jun 1999) |
| 3-l-hydroxykynurenine | An intermediate in the catabolism of l-tryptophan and a precursor of xanthurenate; elevated in cases of a vitamin B6 deficiency. (05 Mar 2000) |
| 3-mercaptolactate | A product of cysteine catabolism; formed by the action of lactate dehydrogenase on 3-mercaptopyruvate that was, in turn, formed by transamination of cysteine; present in normal human urine as a mixed disulfide with cysteine; elevated in the urine in individuals with mercaptolactate-cysteine disulfiduria. (05 Mar 2000) |
| 3-mercaptopropionic acid | <chemical> 3-mercaptopropionic acid. An inhibitor of glutamate decarboxylase. It decreases the gaba concentration in the brain, thereby causing convulsions. Pharmacological action: convulsants, gaba agents, enzyme inhibitors. Chemical name: Propanoic acid, 3-mercapto- (12 Dec 1998) |
| 3-mercaptopyruvate | The transaminated product of cysteine; formed in cysteine catabolism; elevated in individuals with a deficiency of 3-mercaptopyruvate sulfurtransferase. 3-mercaptopyruvate sulfurtransferase, an enzyme that is a part of the cysteine catabolic pathway; it catalyses the conversion of 3-mercaptopyruvate to pyruvate and H2S; a deficiency of this enzyme will result in elevated urine concentrations of 3-mercaptopyruvate as well as of 3-mercaptolactate, both in the form of disulfides with cysteine. (05 Mar 2000) |
| 3-methoxy-4-hydroxymandelic acid | Misnomer for 4-hydroxy-3-methoxymandelic acid (a,3-dihydroxy-2-methoxybenzeneacetic acid);the major urinary metabolite of adrenal and sympathetic catecholamines (e.g., from both epinephrine and norepinephrine); elevated in most patients with pheochromocytoma. Acronym: VMA (05 Mar 2000) |
| 3-methoxy-4-hydroxymandelic acid test | A test for catecholamine-secreting tumours (pheochromocytoma and neuroblastoma) performed on a 24-hr urine specimen; it is based on the fact that vanillylmandelic acid is the major urinary metabolite of norepinephrine and epinephrine. Synonym: 3-methoxy-4-hydroxymandelic acid test, VMA test. (05 Mar 2000) |
| 3-methoxy-4-hydroxyphenylethanol | <chemical> 3-methoxy-4-hydroxyphenylethanol. Metabolite of serotonin and norepinephrine. Chemical name: Benzeneethanol, 4-hydroxy-3-methoxy- (12 Dec 1998) |
| 3-methyl-2-oxobutanoate hydroxymethyltransferase | <enzyme> Methylenetetrahydrofolate and alpha-ketoisovalerate gives tetrahydrofolate and ketopantoate Chemical name: 5,10-methylenetetrahydrofolate alpha-ketoisovalerate hydroxymethyltransferase Registry number: EC 2.1.2.11 Synonym: iphm transferase, panb protein, ketopantoate hydroxymethyltransferase (26 Jun 1999) |
| 3-methylbenzylalcohol dehydrogenase | <enzyme> Involved in m-xylene metabolism by pseudomomas paucimobilis Registry number: EC 1.1.1.- (26 Jun 1999) |