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2-heptaprenyl-1,4-naphthoquinone methyltransferase <enzyme> Catalyses last step of menaquinone biosynthesis; genbank d87054
Registry number: EC 2.1.1.-
Synonym: heppp orf2
(26 Jun 1999)
2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase <enzyme> Catalyses conversion of 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate to 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate; enzyme d of p-cumate catabolic pathway in pseudomonas putida
Registry number: EC 4.1.1.-
Synonym: cmtd gene product
(26 Jun 1999)
2-hydroxy-3-oxoadipate synthase <enzyme> Deficient in hyperoxaluria type i
Registry number: EC 4.1.3.15
Synonym: 2-ketoglutarate-glyoxylate carboligase, glyoxylate-oxoglutarate carboligase, delta-hydroxylaevulinate synthase, 2-oxoglutarate-glyoxylate carboligase, 2-hydroxy-3-oxoadipate carboxylase
(26 Jun 1999)
2-hydroxy-3-oxopropionate reductase <enzyme> Catalyses reversibly the reduction of glycerate to 2-hydroxy-3-oxopropanate in the presence of nad(p+)
Registry number: EC 1.1.1.60
Synonym: tartronate saemialdehyde reductase, tsa reductase
(26 Jun 1999)
2-hydroxy-4-carboxymucconate-6-saemialdehyde dehydrogenase <enzyme> Catalyses alpha-hydroxy-gamma-carboxymuconic-epsilon-saemialdehyde to alpha-hydroxy-gamma-carboxymuconic acid
Registry number: EC 1.2.1.45
Synonym: alpha-hydroxy-gamma-carboxymuconic-epsilon-saemialdehyde dehydrogenase, chms dehydrogenase
(26 Jun 1999)
2-hydroxy-5-nitrobenzyl bromide <chemical> 2-(bromomethyl)-5-nitrophenol. A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as koshland's reagent.
Pharmacological action: indicators and reagents.
Chemical name: Phenol, 2-(bromomethyl)-4-nitro-
(12 Dec 1998)
2-hydroxy-6-oxo-2,4-heptadienoate hydrolase <enzyme> Above cpd hydrolyzed to 2-oxopent-4-enoate (2-hydroxypenta-2,4-dienoate); enzyme e of p-cumate catabolic pathway in pseudomonas putida
Registry number: EC 3.7.-
Synonym: hodh hydrolase, 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase, cmte gene product
(26 Jun 1999)
2-hydroxy-isonicotinic acid hydroxylase <enzyme> Forms 2,6-dihydroxy-isonicotinic acid (citrazinic acid); contains iron and a flavin; incorporates hydroxyl group of water
Registry number: EC 1.-
Synonym: hinah
(26 Jun 1999)
2-hydroxyacid dehydrogenase <enzyme> Requires nad+; deficiency creates l-2-hydroxyglutaric acidemia; do not confuse with EC 1.1.3.15 which uses o2 or EC 1.1.99.2 which uses an unspecified acceptor
Registry number: EC 1.1.1.-
Synonym: l-2-hydroxyacid dehydrogenase, 2-hydroxyglutaric acid dehydrogenase (nad)
(26 Jun 1999)
2-hydroxychromene-2-carboxylate isomerase <enzyme> Catalyses the conversion of 2-hydroxychromene-2-carboxylate to cis-o-hydroxybenzylidenepyruvate--a step in the bacterial degradation of naphthalene to salicylate
Registry number: EC 5.3.99.-
Synonym: o-hydroxychromene-2-carboxylate isomerase, hcca isomerase
(26 Jun 1999)
2-hydroxyglutarate dehydrogenase <enzyme> Converts 2-hydroxyglutarate to 2-oxoglutarate
Registry number: EC 1.1.99.2
Synonym: 2-oxoglutarate reductase
(26 Jun 1999)
2-hydroxyglutaryl-CoA dehydratase <enzyme> From acidaminococcus fermentans; catalyses dehydration of (r)-2-hydroxyglutarate in the presence of acetyl-CoA and glutaconate CoA transferase; forms glutaconyl-CoA, an iron-sulfur enzyme.
Registry number: EC 4.2.1.-
Synonym: 2-hydroxyglutaryl-coenzyme a dehydratase
(26 Jun 1999)
2-hydroxyhepta-2,4-diene-1,7-dioate isomerase <enzyme> Exists as a bifunctional enzyme with 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase (EC 4.1.1.68) in the homoprotocatechuate degradative pathway of E coli.
Registry number: EC 5.3.3.-
Synonym: hhdd isomerase
(26 Jun 1999)
2-hydroxymuconate-saemialdehyde hydrolase <enzyme> Reaction: 2-hydroxymuconate saemialdehyde + h2o = formate + 2-oxopent-4-enoate; from pseudomonas putida; amino acid sequence given in first source
Registry number: EC 3.7.1.9
Synonym: 2-hydroxymuconate-saemialdehyde formylhydrolase, xylf protein
(26 Jun 1999)
2-hydroxymuconic saemialdehyde lyase <enzyme> Forms 2-ketopent-4-enoate plus formate
Registry number: EC 4.1.2.-
Synonym: hydroxymuconic saemialdehyde hydrolase, 2-hydroxymuconic saemialdehyde hydrolase
(26 Jun 1999)
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