| 15-oxoprostaglandin 13-reductase | <enzyme> (5z)-(15s)-11 alpha-hydroxy-9,15-dioxoprostanoate:NAD(p)+ delta(13)-oxidoreductase. An enzyme active in prostaglandin e and f catabolism. It catalyses the reduction of the double bond at the 13-14 position of the 15-ketoprostaglandins and uses NADPH as cofactor. Registry number: EC 1.3.1.48 (12 Dec 1998) |
|---|---|
| 15O | Symbol for oxygen-15. (05 Mar 2000) |
| 16 alpha-hydroxyprogesterone dehydratase | <enzyme> From rat intestinal anaerobic bacteria; forms 16-dehydroprogesterone Registry number: EC 4.2.1.- Synonym: 16 alpha-dehydratase (26 Jun 1999) |
| 16,16-dimethylprostaglandin e2 | <chemical> (5z,11 alpha,13e,15r)-11,15-dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid. A synthetic prostaglandin e analog that protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and growth of experimental tumours. Pharmacological action: anti-ulcer agents. Chemical name: Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-oxo-, (5Z,11alpha,13E,15R)- (12 Dec 1998) |
| 16-dehydroprogesterone reductase | <enzyme> Reduces 16-dehydroprogesterone to 17-isoprogesterone; neither NADH or NADPH with or without flavin nucleotides are used as electron donors Registry number: EC 1.3.99.- Synonym: 16-dhpr (26 Jun 1999) |
| 16-hydroxypalmitic acid hydroxylase | <enzyme> P-450 dependent hydroxylation of 16-hydroxypalmitic acid at the c9 or c10 position in the presence of NADPH and oxygen Registry number: EC 1.14.13.- (26 Jun 1999) |
| 16O | Symbol for oxygen-16. (05 Mar 2000) |
| 16S RNA pseudouridine 516 synthase | <enzyme> Acts only on uridine 516 of e. Coli 16s RNA; amino acid sequence given in first source Registry number: EC 5.4.99.- Synonym: psi516 synthase, rsua gene product (26 Jun 1999) |
| 17 alpha-hydroxyprogesterone aldolase | <enzyme> An enzyme of the lyase class that catalyses the cleavage of the bond between carbons 17 and 20 in 17-alpha hydroxyprogesterone to form delta 4-androstene-3,17-dione, an androgen. It also catalyses the conversion of 17 alpha-hydroxypregnenolone to dehydroepiandrosterone. Chemical name: 17 alpha-hydroxyprogesterone acetaldehyde-lyase Registry number: EC 4.1.2.30 (12 Dec 1998) |
| 17-epitestosterone | 17a-Hydroxyandrost-4-en-3-one; 17a-epimer of testosterone;a biologically inactive steroid found in testes and ovaries; may be a metabolite of 4-androstene-3,17-dione and a precursor of 17a-estradiol. (05 Mar 2000) |
| 17-hydroxycorticosteroid test | A test, dependent on the Porter-Silber reaction, that is used as a measure of adrenocortical function and is performed on urine. Low values are seen in Addison's disease and hypopituitarism; high values are seen in Cushing's syndrome and extreme stress. Synonym: 17-OH-corticoids test, Porter-Silber chromogens test. (05 Mar 2000) |
| 17-hydroxycorticosteroids | <biochemistry> A urine test which measures the amount of 17-hydroxycorticosteroids. A fraction of cortisol is metabolised to 17-hydroxycorticosteroids and excreted in the urine. Conditions that result in increased serum cortisol (Cushing's syndrome and Cushing's disease) will result in elevations in 17-hydroxycorticosteroid levels in the urine. (13 Nov 1997) |
| 17-hydroxylase deficiency syndrome | <syndrome> Congenital deficiency of adrenocortical, and possibly ovarian, steroid C-17a hydroxylase; the resulting excessive secretion of corticosterone and deoxycorticosterone produces hypertension and hypokalaemic alkalosis; absence of aldosterone secretion in such patients may indicate a multiple enzymic deficiency. (05 Mar 2000) |
| 17-hydroxyprogesterone | A hydroxyprogesterone with medical uses similar to that of progesterone. (12 Dec 1998) |
| 17-hydroxysteroid dehydrogenases | <enzyme> A class of enzymes that catalyses the oxidation of 17-hydroxysteroids to 17-ketosteroids. Registry number: EC 1.1.- (12 Dec 1998) |