| nevus, spindle cell | A form of pigmented nevus showing intense melanocytic activity around the dermo-epidermal junction. Large numbers of spindle-shaped melanocytes proliferate downward toward the dermis and usually a large amount of pigment is present. It was first described in 1976 and the bulk of patients reported have been young females with the lesions presenting on the thighs. (12 Dec 1998) |
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| nevus unius lateris | A congenital systematised linear nevus limited to one side of the body or to portions of the extremities on one side; lesions are often extensive, forming wave-like bands on the trunk and spiraling streaks on the extremities. Synonym: linear epidermal nevus. (05 Mar 2000) |
| nevus vascularis | <dermatology> Red or purple-coloured vascular skin markings that develop shortly after birth. Most are usually painless and benign and sharply demarcated from surrounding skin, usually located on the head and neck, and grow rapidly. It is caused by proliferation of immature capillary vessels in active stroma, and is usually present at birth or occurs within the first two or three months of life. Some lesions (cavernous haemangioma) will disappear or become harder to see as the child approaches school age. Localised steroid injections have been used successfully to reduce the size of a birthmark but generally they undergo spontaneous regression and involution without scarring and normally require no treatment. (07 Mar 2000) |
| nevus venosus | A nevus formed of a patch of dilated venules. (05 Mar 2000) |
| Sutton's nevus | A benign, sometimes multiple, melanocytic nevus in which involution occurs with a central brown mole surrounded by a uniformly depigmented zone or halo. Synonym: leukoderma acquisitum centrifugum, Sutton's disease, Sutton's nevus. (05 Mar 2000) |
| systematised nevus | A developmental dysplasia of the skin; extensive, patterned, and usually unilateral. (05 Mar 2000) |
| dysplastic nevus | <syndrome> Clinically atypical nevi (usually exceeding 5 mm in diameter and having variable pigmentation and ill defined borders) with an increased risk for development of non-familial cutaneous malignant melanoma. Biopsies show melanocytic dysplasia. Nevi are clinically and histologically identical to the precursor lesions for melanoma in the b-k mole syndrome. (12 Dec 1998) |
| dysplastic nevus syndrome | <syndrome> Clinically atypical nevi (usually exceeding 5 mm in diameter and having variable pigmentation and ill defined borders) with an increased risk for development of non-familial cutaneous malignant melanoma. Biopsies show melanocytic dysplasia. Nevi are clinically and histologically identical to the precursor lesions for melanoma in the b-k mole syndrome. (12 Dec 1998) |
| intradermal nevus | A nevus in which nests of melanocytes are found in the dermis, but not at the epidermal-dermal junction; benign pigmented nevi in adults are most commonly intradermal. (05 Mar 2000) |
| iris-nevus syndrome | <syndrome> Syndrome of glaucoma, iris atrophy, decreased corneal endothelium, anterior peripheral synechia, and multiple iris nodules. Synonym: Cogan-Reese syndrome, iris-nevus syndrome. (05 Mar 2000) |
| Ito's nevus | Pigmentation of skin innervated by lateral branches of the supraclavicular nerve and the lateral cutaneous nerve of the arm, due to scattered, heavily pigmented, dendritic melanocytes in the dermis. (05 Mar 2000) |
| oral epithelial nevus | An autosomal dominant condition of the oral cavity characterised by soft, white or opalescent, thickened and corrugated folds of mucous membrane; other mucosal sites are occasionally involved simultaneously. Synonym: familial white folded dysplasia, oral epithelial nevus. (05 Mar 2000) |
| organoid nevus | Congenital papillary acanthosis of the epidermis, with hyperplasia of sebaceous glands developing at puberty and presence of apocrine glands in non-apocrine areas of the skin (commonly the scalp). A variety of epithelial tumours may arise from a nevus sebaceus in adult life, most commonly basal cell carcinoma. Synonym: Jadassohn's nevus, organoid nevus. (05 Mar 2000) |
| Ota's nevus | Pigmentation of the conjunctiva and skin around the eye, usually unilateral; seen especially in women of Oriental races. Synonym: Ota's nevus. (05 Mar 2000) |
| epidermic-dermic nevus | A nevus consisting of nests of melanocytes in the basal cell zone, at the junction of the epidermis and dermis, appearing as a slightly raised, small, flat, nonhairy pigmented (brown or black) tumour. Synonym: epidermic-dermic nevus. (05 Mar 2000) |