| Ewing's sarcoma | <oncology, tumour> A malignant primary bone tumour that arises most commonly in the first three decades of life. It is highly malignant (prone to spread) and often requires treatment with some combination of radiation therapy and chemotherapy. (27 Sep 1997) |
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| juxtacortical osteogenic sarcoma | <tumour> A form of osteogenic sarcoma of relatively low malignancy, probably arising from the periosteum and initially involving cortical bone and adjacent connective tissue, which occurs in middle-aged as well as young adults and most commonly affects the lower part of the femoral shaft. Synonym: periosteal sarcoma. (05 Mar 2000) |
| Kaposi sarcoma | <oncology, tumour> A sarcoma of spindle cells mixed with angiomatous tissue. A relatively rare malignant skin tumour that results in multifocal purplish coloured papules or plaques that eventually form nodules. Usually classed as an angioblastic tumour. Seen most commonly in patients who suffer from AIDS. Tumours may also occur within the intestines and lungs. Diagnosis may be confirmed with skin biopsy or upper GI endoscopy. Radiation therapy, cryotherapy and chemotherapy have all been used in the treatment of Kaposi sarcoma. (27 Sep 1997) |
| Kaposi sarcoma associated herpesvirus protease | <enzyme> Genbank af010430 Registry number: EC 3.4.21.- Synonym: kshv protease, human herpesvirus 8 protease (26 Jun 1999) |
| kaposi's sarcoma | <oncology, tumour> A type of vascular cancer characterised by soft purple nodules that usually develop first on the feet and then slowly spread across the skin.This cancer is most often found in people with compromised immune systems, such as AIDS patients. (09 Oct 1997) |
| fascicular sarcoma | <tumour> A malignant neoplasm, believed to be of mesenchymal origin, composed of elongated, spindle-shaped cells. Synonym: fascicular sarcoma. (05 Mar 2000) |
| Kirsten sarcoma virus | <virology> A murine sarcoma inducing retrovirus, generated by passaging a murine erythoblastosis virus in newborn rats. Source of the Ki ras oncogene. (18 Nov 1997) |
| feline leukaemia-sarcoma virus complex | Viruses from cats that induce transmissible leukaemia or transmissible fibrosarcoma in kittens. (05 Mar 2000) |
| feline sarcoma | <oncology, tumour> An oncogene carried by one of the strains of the feline sarcoma virus (the Snyder-Theilen strain, Garden-Rasheed strain, McDonough strain). It causes the development of sarcoma tumours in cats. The normal product of the gene (as a proto-oncogene) seems to be a kinase enzyme that phosphorylates (attaches phosphate groups to) the amino acid tyrosine in polypeptides. (09 Oct 1997) |
| feline sarcoma virus | <virology> A retrovirus which carries an oncogene that causes feline sarcoma (a tumour-causing disease) in cats. (09 Oct 1997) |
| leukocytic sarcoma | <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is classified according of the type leucocyte most prominently involved. (18 Nov 1997) |
| lymphatic sarcoma | <tumour> Obsolete term for lymphosarcoma. (05 Mar 2000) |
| acute yellow atrophy of the liver | A lesion in which there is extensive and rapid death of parenchymal cells of the liver, sometimes with fatty degeneration of the size of the organ; the necrosis may result from fulminant viral infection or chemical poisoning; associated with jaundice. Synonym: acute parenchymatous hepatitis, Rokitansky's disease. (05 Mar 2000) |
| adenoma, liver cell | A benign epithelial tumour of the liver. (12 Dec 1998) |
| alcoholic liver disease | <gastroenterology> Alcoholic cirrhosis is a condition of irreversible liver disease due to the chronic inflammatory and toxic effects of ethanol on the liver. In cirrhosis, the liver cells are replaced by fibrous scar tissue. Fibrosis leads to the development of portal hypertension. The development of cirrhosis is directly related to the duration and quantity of alcohol consumption. The manifestations of cirrhosis are related to the liver's inability to not adequately remove waste products from the bloodstream and the effects of portal hypertension. (15 Nov 1997) |