| WBC | well baby care/clinic; white blood cell; white blood cell count; whole blood cell count |
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| WC | ward clerk; water closet; Weber-Christian [syndrome]; wheel chair; white cell; white cell casts; whi... |
| MEN | Multiple Endocrine Neoplasia ; AD Trait 1. MEN Type I(= Wermer Syndro... |
| NK cell | Natural Killer cell |
| RS cell | Reed Sternberg cell |
| genes, suppressor, tumour | Genes that inhibit expression of the tumourigenic phenotype. They are normally involved in holding cellular growth in check. When tumour suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and deregulated growth is possible. (12 Dec 1998) |
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| genes, wilms' tumour | Tumour suppressor genes located in the 11p13 region on the short arm of human chromosome 11. The absence of these genes is associated with the formation of wilms' tumour. (12 Dec 1998) |
| receptors, tumour necrosis factor | Cell surface receptors that bind tumour necrosis factor and trigger changes which influence the behaviour of cells. The two recognised tumour necrosis factor receptors are designated alpha and beta receptors. Both receptors bind both alpha and beta tumour necrosis factors with high affinity, and both are members of the nerve growth factor receptor family. (12 Dec 1998) |
| Recklinghausen's tumour | A small, circumscribed, benign tumour of the genital tract, composed of small glandlike spaces lined by flattened or cuboidal mesothelium-like cells. (12 Dec 1998) |
| carotid body tumour | An invariably benign, encapsulated, firm round mass at the bifurcation of the common carotid artery, with nests of large polyhedral cells in alveolar or organoid arrangement. It is usually asymptomatic but large masses may encroach upon the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies. (12 Dec 1998) |
| villous tumour | <tumour> A papilloma composed of slender, finger-like excrescences occurring in the bladder or large intestine, or from the choroid plexus of the cerebral ventricles; villous papilloma's of the colon are usually sessile and frequently become malignant. Synonym: villous tumour. (05 Mar 2000) |
| Gleason's tumour grade | A classification of adenocarcinoma of the prostate by evaluation of the pattern of glandular differentiation; the tumour grade, know as Gleason's score, is the sum of the dominant and secondary patterns, each numbered on a scale of 1 to 5. (05 Mar 2000) |
| glomus jugulare tumour | A paraganglioma involving the glomus jugulare, a microscopic collection of chemoreceptor tissue in the adventitia of the bulb of the jugular vein. It may cause paralysis of the vocal cords, attacks of dizziness, blackouts, and nystagmus. It is not resectable but radiation therapy is effective. It regresses slowly, but permanent control is regularly achieved. (12 Dec 1998) |
| glomus tumour | A blue-red, extremely painful paraganglioma involving a glomeriform arteriovenous anastomosis (glomus body), which may be found anywhere in the skin, most often in the distal portion of the fingers and toes, especially beneath the nail. They may also occur in the stomach and nasal cavity. It is composed of specialised pericytes (sometimes termed glomus cells), usually in single encapsulated nodular masses which may be several millimeters in diameter. When located in the usual subungual site, the abundant innervation makes the tumour exquisitely painful; when located elsewhere, the glomus tumour is painless. (12 Dec 1998) |
| pearl tumour | An obsolete term for cholesteatoma. (05 Mar 2000) |
| cellular tumour | A tumour composed mainly of closely packed cells. (05 Mar 2000) |
| cerebellopontine angle tumour | This is a benign tumour of the 8th cranial nerve that affects approximately 1 out of 100,000 people. This tumour arises from the myelin forming Schwann cells that coat the 8th cranial nerve (acoustic nerve). Clinical presentation usually includes hearing deficit. Diagnosis can be made with auditory evoked potentials and/or MRI scanning of the brain. Vertigo and tinnitus may be associated symptoms. Surgical removal of this tumour involves dissection, cautery and obliteration with laser. Causes: acoustic neuroma (90%), meningioma (7%), epidermoid (3%), uncommon: metastasis, trigeminal neuroma, arachnoid cyst, aneurysm, vertebro-basilar dolichoectasia (12 Dec 1998) |
| melanotic neuroectodermal tumour of infancy | A benign neoplasm of neuroectodermal origin that most often involves the anterior maxilla of infants in the first year of life. It presents clinically as a rapidly growing blue-black lesion producing a destructive radiolucency; histologically, it is characterised by small round undifferentiated tumour cells interspersed with larger polyhedral melanin-producing cells arranged in an alveolar configuration. Synonym: melanoameloblastoma, pigmented ameloblastoma, pigmented epulis, progonoma of jaw, retinal anlage tumour. (05 Mar 2000) |
| Godwin tumour | Benign tumour-like masses of lymphoid tissue in the parotid gland, containing scattered small, mainly solid islands of epithelial cells. Synonym: Godwin tumour. (05 Mar 2000) |
| retinal anlage tumour | A benign neoplasm of neuroectodermal origin that most often involves the anterior maxilla of infants in the first year of life. It presents clinically as a rapidly growing blue-black lesion producing a destructive radiolucency; histologically, it is characterised by small round undifferentiated tumour cells interspersed with larger polyhedral melanin-producing cells arranged in an alveolar configuration. Synonym: melanoameloblastoma, pigmented ameloblastoma, pigmented epulis, progonoma of jaw, retinal anlage tumour. (05 Mar 2000) |