| trypsin inhibitors | Serine proteinase inhibitors which inhibit trypsin. They may be endogenous or exogenous compounds. (12 Dec 1998) |
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| trypsinogen | <physiology> The antecedent of trypsin, a substance which is contained in the cells of the pancreas and gives rise to the trypsin. Origin: Trypsin + -gen. Source: Websters Dictionary (01 Mar 1998) |
| tryptamine | 3-(2-Aminoethyl)indole;a decarboxylation product of l-tryptophan that occurs in plants and certain foods (e.g., cheese). It raises the blood pressure through vasoconstrictor action, by the release of norepinephrine at postganglionic sympathetic nerve endings, and is believed to be one of the agents responsible for hypertensive episodes following therapy with monoamine oxidase inhibitors (e.g., pargyline hydrochloride). (05 Mar 2000) |
| tryptamine-strophanthidin | A semisynthetic cardiac glycoside that is a condensation product of strophanthidin and tryptamine; given orally, it has a rapid onset and short duration of cardiac action. (05 Mar 2000) |
| tryptase | <enzyme> Isolated from mouse; prior to 1993 tryptase was indexed as tosylarginine methyl ester hydrolase Pharmacological action: inflammation mediators, mitogens Registry number: EC 3.4.21.59 Synonym: mast cell tryptase 2, mmcp-7, human mast cell tryptase, mast cell protease 7, mast cell tryptase, granzyme k (26 Jun 1999) |
| tryptic | <physiology> Relating to trypsin or to its action; produced by trypsin; as, trypsin digestion. Source: Websters Dictionary (01 Mar 1998) |
| tryptonaemia | The presence of tryptone in the circulating blood. (05 Mar 2000) |
| tryptone | <physiology> The peptone formed by pancreatic digestion; so called because it is formed through the agency of the ferment trypsin. Source: Websters Dictionary (01 Mar 1998) |
| tryptophan | <amino acid> One of the 20 amino acids found in proteins. Essential dietary component in humans. Precursor of nicotinamide. (18 Nov 1997) |
| tryptophan 2,3-dioxygenase | An oxidoreductase catalyzing the reaction of l-tryptophan and O2 to produce l-N-formylkynurenine; an adaptive enzyme, the level (in the liver) being controlled by adrenal hormones; a step in tryptophan catabolism; also, a step in the synthesis of NAD+ from tryptophan. Synonym: pyrrolase, tryptophan oxygenase, tryptophan pyrrolase, tryptophanase. (05 Mar 2000) |
| tryptophan 2-methyltransferase | <enzyme> From streptomyces laurentii; catalyses the transfer of a methyl group from s-adenosylmethionine to the c-2 carbon of tryptophan resulting in alpha-methyltryptophan; involved in the biosynthesis of thiostrepton Registry number: EC 2.1.1.- Synonym: s-adenosylmethionine-tryptophan 2-methyltransferase (26 Jun 1999) |
| tryptophan 2-monooxygenase | <enzyme> Forms indole-3-acetamide Registry number: EC 1.13.12.3 (26 Jun 1999) |
| tryptophan C-methyltransferase | <enzyme> Catalyses transfer of methyl group from s-adenosylmethionine to c-3 of tryptophan resulting in beta-methyltryptophan; involved in streptonigrin biosynthesis Registry number: EC 2.1.1.- (26 Jun 1999) |
| tryptophan decarboxylase | <enzyme> An enzyme that catalyses the decarboxylation of l-dopa to dopamine, of l-tryptophan to tryptamine, and of l-hydroxytryptophan to serotonin; important in the biosynthetic pathway of catecholamines and melanin. Synonym: dopa decarboxylase, hydroxytryptophan decarboxylase, tryptophan decarboxylase. (05 Mar 2000) |
| tryptophan desmolase | <enzyme> An enzyme that catalyses the conversion of l-serine and 1-(indol-3-yl)glycerol 3-phosphate to l-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyses the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. Chemical name: L-Serine hydro-lyase (adding indoleglycerol-phosphate) Registry number: EC 4.2.1.20 (12 Dec 1998) |