| thromboses | Plural of thrombosis. (05 Mar 2000) |
|---|---|
| thrombosin | <enzyme> Protease (34 kD) generated in blood clotting that acts on fibrinogen to produce fibrin. Consists of two chains, A and B, linked by a disulphide bond. B chain has sequence homology with pancreatic serine proteases: cleaves at Arg Gly. Thrombin is produced from prothrombin by the action either of the extrinsic system (tissue factor + phospholipid) or, more importantly, the intrinsic system (contact of blood with a foreign surface or connective tissue). Both extrinsic and intrinsic systems activate plasma factor X to form factor Xa which then, in conjunction with phospholipid (tissue derived or platelet factor 3) and factor V, catalyses the conversion. (18 Nov 1997) |
| thrombosis | <haematology> The formation, development or presence of a thrombus. (14 May 1997) |
| thrombospondin | <cell biology> Homotrimeric glycoprotein (450 kD) from _ granules of platelets and synthesised by various cell types in culture. Also found in extracellular matrix of cultured endothelial, smooth muscle and fibroblastic cells. May have autocrine growth regulatory properties: involved in platelet aggregation. (18 Nov 1997) |
| thrombospondin 1 | An extracellular matrix glycoprotein from platelets and a variety of normal and transformed cells of both mesenchymal and epithelial origin. Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been studied for its use as a potential regulator of tumour growth and metastasis. (12 Dec 1998) |
| thrombospondins | A family of related, adhesive glycoproteins which are synthesised, secreted, and incorporated into the extracellular matrix of a variety of cells, including alpha granules of platelets following thrombin activation and endothelial cells. They interact with a number of blood coagulation factors and anticoagulant factors. Five distinct forms have been identified, thrombospondin 1, -2, -3, -4, and cartilage oligomeric matrix protein (comp). They are involved in cell adhesion, platelet aggregation, cell proliferation, angiogenesis, tumour metastasis, vascular smooth muscle growth, and tissue repair. (12 Dec 1998) |
| thrombostasis | Local arrest of the circulation by thrombosis. Origin: thrombo-+ G. Stasis, a standing (05 Mar 2000) |
| thrombosthenin | <cell biology> Obsolete name for platelet contractile protein: now known to be actomyosin (which makes up 15-20% of the total platelet protein). (18 Nov 1997) |
| thrombotic | Relating to, caused by, or characterised by thrombosis. (05 Mar 2000) |
| thrombotic disease due to protein c deficiency | Protein C is a protein in plasma that enters into the cascade of biochemical events leading to the formation of a clot. Deficiency of protein c results in thrombotic (clotting) disease and excess platelets with recurrent thrombophlebitis (inflammation of the vein that occurs when a clot forms). The clot can break loose and travel through the blood stream (thromboembolism) to the lungs causing a pulmonary embolism, brain causing a stroke (cerebrovascular accident), heart causing an early heart attack, skin causing what in the newborn is called neonatal purpura fulminans, the adrenal gland causing haemorrhage with abdominal pain, abnormally low blood pressure (hypotension), and salt loss. Protein c deficiency is due to possession of one gene (heterozygosity) in chromosome band 2q13-14. The possession of two such genes (homozygosity) is usually lethal. (12 Dec 1998) |
| thrombotic gangrene | Gangrene due to occlusion of an artery by a thrombus. (05 Mar 2000) |
| thrombotic hydrocephalus | Increase in cerebrospinal fluid and of intracranial pressure following thrombosis of the cerebral veins or sinuses; caused by septic infection, dehydration, tuberculosis, typhoid, leukaemia, and other conditions. (05 Mar 2000) |
| thrombotic infarct | An infarct caused by a thrombus. (05 Mar 2000) |
| thrombotic microangiopathy | Thrombosis within small blood vessels, as in thrombotic thrombocytopenic purpura. (05 Mar 2000) |
| thrombotic phlegmasia | An extreme edematous swelling of the leg following childbirth, due to thrombosis of the iliofemoral veins. Synonym: leukophlegmasia dolens, milk leg, puerperal phlebitis, thrombotic phlegmasia, white leg. (05 Mar 2000) |
| thrombosis |
(noun) the formation, development, or existence of a blood clot or thrombus within the vascular system. It is life-saving when it occurs during a hemorrhage. It is life threatening when it occurs at any other time because the clot can occlude a vessel and stop blood supply to an organ or a part. The thrombus, if detached becomes an embolus and occludes a vessel at a distance from the original site
출처: www.orgsites.com/fl/adjuvantdisease/_pgg9.php3
|
|---|---|
| thromboembolism |
(noun) the blocking of a blood vessel by a thrombus (blood clot) that has become detached from its site of formation
출처: www.orgsites.com/fl/adjuvantdisease/_pgg9.php3
|
| thrombocyte |
Also called a platelet. Component of blood that aids in clotting.
출처: www.clevelandclinic.org/heartcenter/pub/glossary/t...
|
| thromboplastin |
THROM-bo-PLAS-tin A protein released from blood vessel walls following injury that converts prothrombin to thrombin. 717
출처: www.mhhe.com/biosci/genbio/life/glossaryt.mhtml
|
| thrombosis |
the inappropriate or pathological formation of a solid mass (from the constiutents of blood) within a blood vessel or organ.
출처: www.uwo.ca/pathol/glossary.html
|