| NT | nasotracheal; neotetrazolium; neurotensin; neurotrophic; neutralization test; nicotine tartrate; non... |
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| Nt | amino terminal |
| pFc | noncovalently bonded dimer of the C-terminal immunoglobulin of the Fc fragment |
| TA | alkaline tuberculin; arterial tension; axillary temperature; tactile afferent; Takayasu arteritis; t... |
| TAC | tachykinin; terminal antrum contraction; tetracaine, adrenalin, and cocaine; time-activity curve; to... |
| terminal transferase | <enzyme> An enzyme adds a particular nucleotide to the 3' end of DNAstrands. (09 Oct 1997) |
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| terminal transferases | Enzymes that covalently add nucleotides to the 3' end of polynucleic acids; e.g., DNA nucleotidylexotransferase. (05 Mar 2000) |
| terminal vein | <anatomy, vein> A long vein passing forward in the groove between the thalamus and caudate nucleus, covered by the lamina affixa, receiving the transverse caudate veins along its lateral side, and joining at the caudal wall of Monro's foramen with the choroidal vein and vein of septum pellucidum to form the internal cerebral vein. Synonym: vena terminalis, vena thalamostriata superior, terminal vein, vein of corpus striatum. (05 Mar 2000) |
| terminal ventricle | A dilation of the central canal of the spinal cord at the tip of the medullary cone. Synonym: ventriculus terminalis. (05 Mar 2000) |
| terminal web | <cell biology> The cytoplasmic region at the base of microvilli in intestinal epithelial cells, a region rich in microfilaments from the microvillar core and from adherens junctions, in myosin and in other proteins characteristic of an actomyosin motor system. (13 Jan 1998) |
| termino-terminal anastomosis | An operation by which the central end of an artery is connected with the peripheral end of the corresponding vein, and the peripheral end of the artery with the central end of the vein. (05 Mar 2000) |
| functional terminal innervation ratio | The number of muscle fibres divided by the number of axons that innervate them. (05 Mar 2000) |
| long-terminal repeat | <molecular biology> Identical DNA sequences, several hundred nucleotides long, found at either end of transposons and the proviral DNA, formed by reverse transcription of retroviral RNA. They are thought to have an essential role in integrating the transposon or provirus into the host DNA. Long terminal repeats have inverted repeats, that is, sequences close to either end are identical when read in opposite directions. In proviruses the upstream long-terminal repeat acts as a promoter and enhancer and the downstream long-terminal repeat as a polyadenylation site. Acronym: LTR (15 Nov 1997) |
| long terminal repeat sequences | Regions of the RNA genome associated with regulation, integration, and expression of retroviruses. (05 Mar 2000) |
| acetyl-activating enzyme | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
| acyl-activating enzyme | <enzyme> Fatty acid thiokinase (long-chain), a ligase forming acyl-CoA, AMP, and pyrophosphate from long-chain fatty acids, ATP, and coenzyme A. Activity is independent of phosphatidylcholine Registry number: EC 6.2.1.3 Synonym: acyl-activating enzyme, dodecanoyl-CoA synthetase, fatty acid thiokinase (long chain), acid-coenzyme a ligase, fatty acid-CoA ligase, acyl-CoA synthetase, acyl-CoA ligase, coash ligase, ciprofibroyl-CoA synthetase, pristanoyl-CoA synthetase, palmityl CoA synthetase, palmitoyl CoA synthetase, palmitoyl CoA ligase, fatty acyl-CoA synthetase, very long chain fatty acid acyl-CoA synthetase, vlcfa acyl-CoA synthetase, nafenopin-CoA ligase, palmitoyl-CoA synthase, faa2 gene product, faa2p protein, vlacs enzyme (26 Jun 1999) |
| adaptive enzyme | Inducible enzyme, an enzyme that can be detected in a growing culture of a microorganism, after the addition of a particular substance (inducer) to the culture medium, but was not detectable prior to the addition and can act on the inducer. A prototype is the beta-galactosidase of Escherichia coli, synthesised upon the addition of various galactosides, whether or not these are good substrates. Compare: constitutive enzyme. Synonym: adaptive enzyme. (05 Mar 2000) |
| allosteric enzyme | <biochemistry, chemistry> A regulatory enzyme whose activity is modified by the noncovalent binding of a particular metabolite at a site (the allosteric site) other than the active site. (09 Oct 1997) |
| amino acid activating enzyme | <enzyme> Enzymes catalyzing the formation of a specific aminoacyl-tRNA from an amino acid and adenosine 5'-triphosphate with the concomitant formation of adenosine 5'-monophosphate and pyrophosphate. Synonym: amino acid activating enzyme, aminoacyl-tRNA ligases. (05 Mar 2000) |
| angiotensin-converting enzyme | <enzyme> This hydrolase enzyme cleaves the decapeptide angiotensin I (biologically inactive) to form active angiotensin II by angiotensin-converting enzyme which removes a dipeptide (histidylleucine) from angiotensin I. Angiotensin II causes contraction of vascular smooth muscle and thus raises blood pressure and stimulates aldosterone release from the adrenal glands. Angiotensin is finally broken down by angiotensinases. Elevations in angiotensin converting enzyme are seen sarcoidosis, histoplasmosis, alcoholic cirrhosis, asbestosis, berylliosis, diabetes, Hodgkin's disease, hyperthyroidism, amyloidosis, primary biliary cirrhosis, idiopathic pulmonary fibrosis, pulmonary embolism, scleroderma, silicosis, tuberculosis, Gaucher's disease and leprosy. The normal values are 18 to 67 U/ml over 20 years of age (people under 20 have higher levels). Drugs that inhibit ACE are used to treat hypertension and congestive heart failure. See: angiotensin-converting enzyme inhibitor Acronym: ACE (12 Aug 2000) |
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