| PEPC proteinase | <enzyme> 553 amino acid protein from aspergillus niger; has a putative signal sequence for transport into the endoplasmic reticulum; protein is made as a large precursor which is matured by cleavage of 130-40 amino acids from its n terminus and appr. 70 amino acids from its c terminus; amino acid sequence given in first source Registry number: EC 3.4.21.- Synonym: pepc gene product (26 Jun 1999) |
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| ribosomal neutral proteinase | <enzyme> Ribosomal serine proteinase from rat liver ribosomes in cryptic form Registry number: EC 3.4.21.52 Synonym: cathepsin r (26 Jun 1999) |
| Clostridium histolyticum proteinase B | A cysteine proteinase cleaving preferentially at the carboxyl side of arginyl and lysyl residues. It also has an esterase activity. Synonym: clostridiopeptidase B, Clostridium histolyticum proteinase B. (05 Mar 2000) |
| MSP 1 proteinase | <enzyme> Basic serine proteinase from bothrops moojeni (caissaca) venom; causes platelet aggregation Registry number: EC 3.4.21.- Synonym: caissaca msp 1 proteinase (26 Jun 1999) |
| MSP 2 proteinase | <enzyme> Basic serine protease from bothrops moojeni (caisacca) venom; has much higher tame hydrolase activity than msp 1; but does not have platelet aggregation activity Registry number: EC 3.4.21.- Synonym: caissaca msp 2 proteinase (26 Jun 1999) |
| H(2)-proteinase | <enzyme> From habu snake, trimeresurus flavoviridis; non-haemorrhagic, non-glycosylated protein consisting of 201 amino acids; mw 23 kD; has typical zn-chelating sequence Registry number: EC 3.4.24.- Synonym: h2-proteinase h2-proteinase, trimeresurus (26 Jun 1999) |
| cysteine proteinase | <enzyme> An enzyme that destroys proteins by hydrolysis, turning them back into individual amino acids. (09 Oct 1997) |
| cysteine proteinase inhibitors | Exogenous and endogenous compounds which inhibit cysteine proteinases. (12 Dec 1998) |
| proteinase | <enzyme> An enzyme that cleaves protein at positions within the chain. Formally, the enzymes are peptidyl peptide hydrolases, more usually known as proteinases or proteolytic enzymes. (18 Nov 1997) |
| proteinase inhibitor inducing factor | See: PIIF. (18 Nov 1997) |
| human a1-proteinase inhibitor | A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of alterations in the amino acid and sialic acid components of the glycoprotein. A1-Antitrypsin also inhibits thrombin. Synonym: a1-trypsin inhibitor, human a1-proteinase inhibitor. (05 Mar 2000) |
| SIV(mac) proteinase | <enzyme> From macaque simian immunodeficiency virus; has 80% homology with hiv protease Registry number: EC 3.4.23.- Synonym: siv mac proteinase, sivmac proteinase siv protease (26 Jun 1999) |
| snake proteinase | <enzyme> Amino acid sequence given in first source Registry number: EC 3.4.21.- Synonym: snake gene product, snake protein, snake protease (26 Jun 1999) |
| SP220K cell surface matrix proteinase | <enzyme> Inactive form has guanidinobenzoatase activity; active form has gelatinolytic activity Registry number: EC 3.4.21.- Synonym: sp220k enzyme (26 Jun 1999) |
| Staphylococcus aureus neutral proteinase | <enzyme> Included in the group of microbial metalloproteinases EC 3.4.24.4; ptrb protein is isolated from E coli; sakstar is recombinant staphylokinase Pharmacological action: fibrinolytic agents Registry number: EC 3.4.24.- Synonym: protease II, staphylokinase, staph aureus protease, staphylococcal protease, E coli protease, ptrb protein, sakstar, (26 Jun 1999) |