| TTP | Thrombotic Thrombocytopenic Purpura |
|---|---|
| AITP | autoimmune idiopathic thrombocytopenic purpura |
| ATP | adenosine triphosphate; ambient temperature and pressure; autoimmune thrombocytopenic purpura |
| CPP | cancer proneness phenotype; canine pancreatic polypeptide; cerebral perfusion pressure; chest pain p... |
| HGP | hepatic glucose production; hyperglobulinemic purpura |
| idiopathic thrombocytopenia purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
|---|---|
| idiopathic thrombocytopenic purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
| immune thrombocytopenic purpura | <haematology> A low number of platelets in the blood, which is common in people with HIV, but often resolves as immune deficiency worsens. HIV-related ITP usually does not have serious consequences. Its cause has not been definitely determined. Treatment with AZT frequently alleviates the condition. (09 Oct 1997) |
| thrombocytopenia purpura | <haematology> In severe thrombocytopenia, bleeding into skin leads to small petechial haemorrhages. Primary thrombocytopenia purpura is of unknown cause but results from an autoimmune mechanism that causes platelet destruction. Secondary thrombocytopenic purpura may result from drug-induced type II hypersensitivity in which platelets coated with antibody to the drug (which is acting as a hapten) are destroyed in a complement mediated reaction. It can also follow a viral upper respiratory infection and may be seen in association with lupus. (15 Oct 1997) |
| thrombocytopenic purpura | See: idiopathic thrombocytopenic purpura. (05 Mar 2000) |
| thrombopenic purpura | idiopathic thrombocytopenia purpura |
| thrombotic thrombocytopenic purpura | A rapidly fatal or occasionally protracted disease with varied symptoms in addition to purpura, including signs of central nervous system involvement, due to formation of fibrin or platelet thrombi in arterioles and capillaries in many organs. Synonym: Moschcowitz' disease. (05 Mar 2000) |
| equine nonthrombocytopenic purpura | <veterinary> An immune-mediated vasculitis of horses due to immune complex deposition, characteristically as a sequela of strangles. (05 Mar 2000) |
| factitious purpura | Self-induced, often painful, ecchymoses. (05 Mar 2000) |
| fibrinolytic purpura | Purpura in which the bleeding is associated with rapid fibrinolysis of the clot. (05 Mar 2000) |