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  • Proto-Oncogene Proteins c-maf - »õâ Maf proto-oncogene protein is the major cellular homolog of the V-MAF ONCOGENE PROTEIN. It was the first mammalian MAF TRANSCRIPTION FACTOR identified, and it is induced in activated T-LYMPHOCYTES and regulates GENETIC TRANSCRIPTION of INTERLEUKIN-4. c-maf is frequently translocated to an immunoglobulin locus in MULTIPLE MYELOMA.
    Synonyms : Proto-Oncogene Protein c-maf, c-maf Proto-Oncogene Protein, Proteins c-maf, Proto-Oncogene, Proto Oncogene Protein c maf, Proto Oncogene Proteins c maf, Proto-Oncogene Protein, c-maf, Proto-Oncogene Protein, maf, c-maf, Proto-Oncogene Protein
  • Proto-Oncogene Proteins c-mdm2 - »õâ An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF.
    Synonyms : Double Minute 2 Protein, MDMX Protein, Mdm-2 Protein, Murine Double Minute 2 Protein, Mdm 2 Protein, Proto Oncogene Proteins c mdm2, Proto-Oncogene Protein, c-mdm2, c mdm2 Proto Oncogene Protein, c-mdm2, Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-met - »õâ Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consists of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations of the gene for PROTO-ONCOGENE PROTEINS C-MET are associated with papillary renal carcinoma and other neoplasia.
    Synonyms : Receptor, HGF, Receptor, Hepatocyte Growth Factor, Receptor, Scatter Factor, Scatter Factor Receptor, Proto Oncogene Proteins c met, Proto-Oncogene Proteins, met, c met Proteins, met Proto Oncogene Proteins
  • Proto-Oncogene Proteins c-mos - »õâ Cellular proteins encoded by the c-mos genes (GENES, MOS). They function in the cell cycle to maintain MATURATION PROMOTING FACTOR in the active state and have protein-serine/threonine kinase activity. Oncogenic transformation can take place when c-mos proteins are expressed at the wrong time.
    Synonyms : Proto-Oncogene Products c-mos, Proto-Oncogene Proteins mos, mos Proto-Oncogene Product pp39, pp39 c-mos, Products c-mos, Proto-Oncogene, Proteins c-mos, Proto-Oncogene, Proteins mos, Proto-Oncogene, Proteins, c-mos, Proteins, mos Proto-Oncogene, c mos Proteins
  • Proto-Oncogene Proteins c-myb - »õâ Cellular DNA-binding proteins encoded by the myb gene (GENES, MYB). They are expressed in a wide variety of cells including thymocytes and lymphocytes, and regulate cell differentiation. Overexpression of myb is associated with autoimmune diseases and malignancies.
    Synonyms : Proto-Oncogene Products c-myb, Proto-Oncogene Protein myb, Proto-Oncogene Proteins myb, c-myb Protein, Proto Oncogene Products c myb, Proto Oncogene Protein myb, Proto Oncogene Proteins c myb, Proto Oncogene Proteins myb, Proto-Oncogene Proteins, myb
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