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pernicious a. a type of megaloblastic anemia usually seen in older adults, caused by impaired intestinal absorption of vitamin B12 due to lack of availability of intrinsic factor; it is often characterized by pallor, achlorhydria, glossitis, gastric mucosal atrophy, weakness, antibodies against gastric parietal cells or intrinsic factor, and neurologic manifestations.
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pernicious m. falciparum m.
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pernicious v. vomiting in pregnancy, so severe as to threaten the life of the mother.
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pernicious anemia A blood disorder caused by a lack of vitamin B12. Patients who have this disorder do not produce the substance in the stomach that allows the body to absorb vitamin B12.
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pernicious anemia a potentially dangerous form of anemia, usually caused by an autoimmune process, which results in a deficiency of vitamin B-12.
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