| GARS | glycine amide phosphoribosyl synthetase |
|---|---|
| GCS | general clinical services; Gianotti-Crosti syndrome; Glasgow Coma Scale; glucocorticosteroid; glutam... |
| GGCS | gamma-glutamyl cysteine synthetase |
| GS | gallstone; Gardner syndrome; gastric shield; general surgery; gestational score; Gilbert syndrome; g... |
| GSD | genetically significant dose; Gerstmann-Straussler disease; glutathione synthetase deficiency; glyco... |
| islet amyloid peptide | <hormone, protein> Peptide of 37 amino acids that selectively inhibits insulin stimulated glucose uptake in muscle. Structurally related to calcitonin gene-related peptide. (15 Oct 1997) |
|---|---|
| eosinophil chemotactic peptide | <protein> Tetrapeptides (of which two are identified: VGSE and AGSE) released by mast cells and that are said to both attract and activate eosinophils. (18 Nov 1997) |
| UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase | <enzyme> Responsible for the addition of o-linked n-acetylglucosamine to proteins Registry number: EC 2.4.1.- Synonym: udp-glcnac-peptide-glcnac-transferase, glcnac transferase (26 Jun 1999) |
| formyl peptide | <biochemistry> Informal term for small peptides with a formylated N terminal methionine and usually a hydrophobic amino acid at the carboxy terminal end (fMetLeuPhe is the most commonly used). These peptides stimulate the motor and secretory activities of leucocytes, particularly neutrophils and monocytes, that have a specific receptor (about 60 kD) of high affinity (Kd approximately 10exp 8M). Leucocytes show chemotaxis towards formyl peptides but the term chemotactic peptides understates the range of activities the molecules will trigger. Thought to be synthetic analogues of bacterial signal sequences though this is unproven. The leucocytes of many animals (e.g. Pig, cow, chicken) do not respond. (18 Nov 1997) |
| leader peptide | <molecular biology> In the regulation of gene expression for enzymes concerned with amino acid synthesis in prokaryotes, the leader sequence codes for the leader peptide that contains several residues of the amino acid being regulated. Transcription is closely linked to translation and if translation is retarded by limited supply of amino acyl tRNA for the specific amino acid, the mode of transcription of the leader sequence permits full transcription of the operon genes, otherwise complete transcription of the leader sequence prematurely terminates transcription of the operon. (18 Nov 1997) |
| acetoacetyl-CoA synthetase | <enzyme> Catalyses the conversion of acetoacetate and CoA in the presence of ATP to yield AMP, pyrophosphate and acetoacetyl-CoA; the latter is the first intermediate in cholesterogenesis; also acts more slowly on l-3-hydroxybutanoate Registry number: EC 6.2.1.16 Synonym: acetoacetyl-CoA ligase, acetoacetate-CoA ligase, acetoacetyl-coenzyme a synthetase (26 Jun 1999) |
| acetyl-CoA synthetase | A ligase that catalyses the reaction of acetate and CoA and ATP to form AMP, pyrophosphate, and acetyl-CoA. A key step in the activation of acetate. Synonym: acetate thiokinase, acetate-CoA ligase, acetyl-activating enzyme, acetyl-CoA synthetase. (05 Mar 2000) |
| acid cholesterol ester synthetase | <enzyme> Aortal enzyme, does not require exogenous ATP or CoA; reverse reaction of cholesterol esterase Registry number: EC 3.1.1.- Synonym: cholesterol ester synthetase (26 Jun 1999) |
| acyl-CoA synthetase | General term for enzymes that form acyl-CoA, now called ligases, specifically, long-chain fatty acid-CoA ligase. (05 Mar 2000) |
| acyl protein synthetase | <enzyme> Component of the fatty acid reductase complex of luminescent bacteria Registry number: EC 2.3.1.- Synonym: luxe gene product, fatty acyl-protein synthetase (26 Jun 1999) |
| aerobactin synthetase | <enzyme> Condenses 2 molecules of n-epsilon-acetyl-n-epsilon-hydroxylysine with citric acid to form aerobactin Registry number: EC 4.1.3.- (26 Jun 1999) |
| alamethicin synthetase | <enzyme> ATP-dependent, similar to gramicidin s synthesis Registry number: EC 6.3.2.- (26 Jun 1999) |
| alpha-aminoadipyl-cysteinyl-valine synthetase | <enzyme> As of 9/27/95 this has been separated from isopenicillin n synthetase Registry number: EC 6.3.2.- Synonym: acv synthetase, aa-cysteine synthetase, delta-(alpha-aminoadipyl)-cys-val synthetase, delta-(l-alpha-aminoadipyl)-l-cyteinyl-d-valine synthetase, pcbab gene product, acva gene product (26 Jun 1999) |
| androsta-5,16-dien-3 beta-ol synthetase | <enzyme> Nadph- and o(2)-dependent; converts progesterone to 4,16-androstadien-3-one and converts pregnenolone to androstadienol Registry number: EC 1.- Synonym: pregnenolone side-chain cleavage enzyme, 5,16-androstadien-3 beta-ol synthetase, 5,16-androstadien-3-ol synthase, 4,16-androstadien-3-one synthesizing enzyme, 4,16-adien-3-one synthase, 4,16-ado synthase, delta(16)-c(19)-steroid synthetase, andien-beta-synthetase, 16-ene-synthetase (26 Jun 1999) |
| apiin synthetase | <enzyme> Transfers d-apiose from udpapiose to 4',5-dihydroxyflavon-7-yl beta-d-glucopyranoside Registry number: EC 2.4.2.- (26 Jun 1999) |