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GRP Gastrin-Releasing Peptide
IAPP Insulinoma Amyloid Poly-Peptide
VIP Vasoactive Intestinal (Poly)Peptide
ANP acute necrotizing pancreatitis; adult nurse practitioner; ancillary nursing personnel; A-norprogeste...
APP acute phase protein; alum-precipitated pyridine; aminopyrazolopyrimidine; amyloid peptide precursor;...
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PIC pre-initiation complex
TIS transcription initiation site
AEF Allogeneic effect factors
APF Anti-perinuclear factors
CF Clastogenic factors
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epidemiologic factors Events, characteristics, or other definable entities that have the potential to bring about a change in a health condition or other defined outcome.
(12 Dec 1998)
essential food factors Those substances required in the diet: certain amino acids and unsaturated fatty acids, vitamins, essential minerals, etc.
(05 Mar 2000)
Factors I XII <haematology> Blood clotting factors, especially from humans. These factors form a cascade in which the activation of the first factor leads to enzymic attack on the next factor and so on, finally resulting in blood clotting.
(18 Nov 1997)
uncoupling factors Substances such as dinitrophenol that allow oxidation in mitochondria to proceed without the usual concomitant phosphorylation to produce ATP; these poisons thus "uncouple" oxidation and phosphorylation.
Synonym: uncoupling factors.
(05 Mar 2000)
lactose factors Plasmids which determine the ability of a bacterium to ferment lactose.
(12 Dec 1998)
LE factors Antinuclear immunoglobulins in plasma of persons with disseminated lupus erythematosus, associated with positive LE tests.
(05 Mar 2000)
leukocyte migration-inhibitory factors Protein factor(s) released by sensitised lymphocytes (and possibly other cells) that inhibit the movement of leukocytes, especially polymorphonuclear cells, away from their site of release. Assays for these factors are used as tests for cellular immunity. Two of the common assays are the leukocyte migration capillary tube technique (lmct) and the leukocyte migration agarose technique (lmat).
(12 Dec 1998)
alpha-aminoacyl-peptide hydrolases <enzyme> Registry number: EC 3.4.11.
(12 Dec 1998)
anionic neutrophil activating peptide <cytokine> A cytokine that activates neutrophils and attracts neutrophils and T-lymphocytes.
It is released by several cell types including monocytes, macrophages, T-lymphocytes, fibroblasts, endothelial cells, and keratinocytes by an inflammatory stimulus. Il-8 is a member of the beta-thromboglobulin superfamily and structurally related to platelet factor 4.
Acronym: IL-8
(12 Dec 1998)
antibiotics, peptide Antibiotics whose structure contains one or more peptides, usually cyclic. They are generally effective against gram-positive bacteria and act by inhibiting peptidoglycan synthesis in bacterial cell walls.
(12 Dec 1998)
atrial natriuretic peptide <hormone> This cardiac hormone (28 amino acid residues) regulates salt and water balance in body fluids and blood pressure, it has potential as a medication to treat heart and kidney failure and the buildup of excess fluid in tissue.
(09 Oct 1997)
bradykinin-potentiating peptide <chemical> 2-l-tryptophan-3-de-l-leucine-4-de-l-proline-8-l-glutamine bradykinin potentiator b. A synthetic nonapeptide with the sequence pyr-trp-pro-arg-pro-gln-ile-pro-pro, which is identical to that of the peptide from the venom of the snake, bothrops jararaca. It acts as an inhibitor of kininase II and angiotensin I and has been proposed as an antihypertensive agent.
Pharmacological action: angiotensin-converting enzyme inhibitors, antihypertensive agents.
Chemical name: Bradykinin potentiator B, 2-L-tryptophan-3-de-L-leucine-4-de-L-proline-8-L-glutamine-
(12 Dec 1998)
brain natriuretic peptide <hormone, protein> Brain peptide that induces diuresis, related to atrial natriuretic peptide.
(18 Nov 1997)
calcitonin gene-related peptide <protein> A second product transcribed from the calcitonin gene. Calcitonin gene related peptide is found in a number of tissues including nervous tissue. It is a vasodilator that may participate in the cutaneous triple response.
It is a neuropeptide of 37 amino acids with structural homology to salmon calcitonin. Co-localises with substance P in neurons. It occurs as a result of alternative processing of mRNA from the calcitonin gene.
The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator.
Intracerebral administration leads to a rise in noradrenergic sympathetic outflow, a rise in blood pressure and a fall in gastric secretion.
Acronym: CGRP
(05 May 2002)
vasoactive intestinal peptide <gastroenterology, protein> Peptide of 28 amino acids, originally isolated from porcine intestine, but later found in the central nervous system where it acts as a neuropeptide and is released by specific interneurons. May also affect behaviour of cells of the immune system.
Acronym: VIP
(05 Jan 1998)
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