| mixed lymphocyte culture | <investigation> Test to determine whether a patients and donor's white blood cells interact adversely. Often used to determine whether a person would be a suitable bone marrow donor for a particular patient. (16 Dec 1997) |
|---|---|
| mixed lymphocyte culture test | Measure of histocompatibility at the hl-a locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way mlc test, the lymphocytes from one of the individuals are inactivated (usually by treatment with mitomycin c or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens. (12 Dec 1998) |
| mixed lymphocyte reaction | <haematology, immunology, investigation> Reaction of mitogenesis produced in T lymphocytes when allogeneic (i.e. Mixed) lymphocytes are brought together, provided they are mismatched in histocompatibility loci. Once used as a test for possible graft compatibility in human grafting. Now known that a negative reaction is a poor predictor of graft acceptance. (18 Nov 1997) |
| mixed mesodermal tumour | A sarcoma of the body of the uterus arising in older women, composed of more than one mesenchymal tissue, especially including striated muscle cells. Synonym: malignant mixed mullerian tumour. (05 Mar 2000) |
| mixed nerve | <anatomy, nerve> A nerve containing both afferent and efferent fibres. (05 Mar 2000) |
| mixed opioid agonist-antagonist | <pharmacology> A compound that has an affinity for two or more types of opioid receptors and blocks opioid effects on one receptor type while producing opioid effects on a second receptor type. (13 Nov 1997) |
| mixed paralysis | Combined motor and sensory paralysis. (05 Mar 2000) |
| mixed sleep apnoea | <chest medicine> A form of sleep apnoea where there is exists a combination of obstructive and central sleep apnoea syndromes. (13 Nov 1997) |
| mixed thrombus | A laminated thrombus, the layers of different ages being of different colour or consistency. Synonym: stratified thrombus. (05 Mar 2000) |
| mixed tide | <ecology, marine biology> Tidal cycle in which there are usually two high and two low tides during a day. (13 Nov 1997) |
| mixed tumour | A tumour composed of two or more varieties of tissue. (05 Mar 2000) |
| mixed tumour, malignant | A malignant tumour composed of more than one type of neoplastic tissue. (12 Dec 1998) |
| mixed tumour, mesodermal | A sarcoma of the body of the uterus arising in older women, composed of more than one mesenchymal tissue, especially including striated muscle cells. It is associated with previous pelvic radiation exposure in 20% of patients. (12 Dec 1998) |
| mixed tumour, mullerian | A tumour, basically a carcinoma with a single sarcoma such as leiomyosarcoma or angiosarcoma or multiple sarcomas of uterine origin. The role of oestrogen has been postulated as a possible aetiological factor in this tumour. (holland et al., cancer medicine, 3d ed, p1703) (12 Dec 1998) |
| mixed tumour of salivary gland | A tumour composed of salivary gland epithelium and fibrous tissue with mucoid or cartilaginous areas. Synonym: pleomorphic adenoma. (05 Mar 2000) |