| Gaucher disorder | <disease> A chronic congenital disease of lipid metabolism caused by a deficiency of the beta-glucocerebrosidase enzyme. The defect is most common in Ashkenazi Jews. Clinical features are hepatosplenomegaly (enlargement of liver and spleen) and in severe early onset forms of the disease, with neurological dysfunction. Inheritance: autosomal recessive. (27 Sep 1997) |
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| gene disorder | Hereditary disorder caused by a mutant allele of a single gene (e.g., Duchenne muscular dystrophy, retinoblastoma, sickle cell disease). Compare polygenic disorders. (05 Mar 2000) |
| manic-depressive disorder | An obsolete term for one of the mood disorders; i.e., bipolar disorder, depression; affective psychosis, affective disorder, bipolar disorder, and endogenous depression. (05 Mar 2000) |
| generalised anxiety disorder | Chronic, repeated episodes of anxiety reactions; a psychological disorder in which anxiety or morbid fear and dread accompanied by autonomic changes are prominent features. See: anxiety. (05 Mar 2000) |
| reactive attachment disorder | Markedly disturbed and developmentally inappropriate social relatedness that begins before age 5 and is associated with grossly pathological child care. The child may persistently fail to initiate and respond to social interactions in a developmentally appropriate way (inhibited type) or there may be a pattern of diffuse attachments with nondiscriminate sociability (disinhibited type). (12 Dec 1998) |
| paranoid disorder | A false belief, seen most often in psychosis (for example schizophrenia). (27 Sep 1997) |
| paranoid personality disorder | A personality disorder characterised by the avoidance of accepting deserved blame and an unwarranted view of others as malevolent. The latter is expressed as suspiciousness, hypersensitivity, and mistrust. (12 Dec 1998) |
| passive-aggressive personality disorder | A personality disorder characterised by an indirect resistance to demands for adequate social and occupational performance; anger and opposition to authority and the expectations of others that is expressed covertly by obstructionism, procrastination, stubbornness, dawdling, forgetfulness, and intentional inefficiency. (12 Dec 1998) |
| visceral disorder | Nomenclature used in reference to psychosomatic disorder. (05 Mar 2000) |
| REM behaviour disorder | A disorder characterised by lack of the atonia of voluntary muscles that normally occurs in REM sleep. (05 Mar 2000) |
| memory disorder | Disturbances in registering an impression, in the retention of an acquired impression or in the recall of an impression. (12 Dec 1998) |
| character disorder | A term referring to a group of behavioural disorder's, now replaced by a more general term, personality disorder, of which character disorder's are now a subclass. (05 Mar 2000) |
| mental disorder | A psychological syndrome or behavioural pattern that is associated with either subjective distress or objective impairment. See: mental illness, behaviour disorder. (05 Mar 2000) |
| grandiose type of paranoid disorder | A delusion in which the person believes that he or she possesses some great but unrecognised talent or insight, or has made an important discovery, with subsequent efforts toward official or public recognition. (05 Mar 2000) |
| persecutory type of paranoid disorder | One of the most common of the types of paranoid disorders, it involves a single theme or series of connected themes, such as being conspired against, cheated, spied on, followed, poisoned or drugged, maligned, harassed, or obstructed in the pursuit of long-term goals; small slights may be exaggerated and become the focus of a delusional system. See: paranoia. Compare: paranoid personality disorder. (05 Mar 2000) |