| sarcoma, kaposi | A multicentric, malignant neoplastic vascular proliferation characterised by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumours have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in jewish and italian males in europe and the united states. An aggressive variant in young children is endemic in some areas of africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in aids patients. Hhv-8 is the suspected cause. (12 Dec 1998) |
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| sarcoma, small cell | A sarcoma characterised by the presence of small cells, cells measuring 9-14 micrometers with a faint or indistinct rim of cytoplasm and an oval-to-elongated nucleus with relatively dense chromatin. (12 Dec 1998) |
| sarcoma, synovial | A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumour can occur in the abdominal wall and other trunk muscles. There are two recognised types: the monophasic (characterised by sheaths of monotonous spindle cells) and the biphasic (characterised by slit-like spaces or clefts within the tumour, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (12 Dec 1998) |
| sarcoma viruses, avian | Species of avian type c retroviruses (retroviruses type c, avian) producing sarcomata and other tumours in chickens and other fowl and also in pigeons, ducks, and rats. (12 Dec 1998) |
| sarcoma viruses, simian | Species of mammalian type c retroviruses (retroviruses type c, mammalian) producing tumours in primates. Originally isolated from a fibrosarcoma in a woolly monkey, ssv is a replication-defective v-onc virus which carries the sis oncogene. In order to propagate, ssv requires a replication-competent helper virus, simian sarcoma virus-associated virus (ssav). (12 Dec 1998) |
| pulmonary artery sarcoma | <radiology> Rare, age: 21 - 80 (most common: 45 - 55), usual presentation: hilar mass or hilar infiltrative lesion, other findings: decreased vascular markings, atelectasis / volume loss, metastatic nodules, decreased or absent perfusion on V/Q, intravascular soft-tissue mass on CT (12 Dec 1998) |
| soft tissue sarcoma | A sarcoma that begins in the muscle, fat, fibrous tissue, blood vessels, or other supporting tissue of the body. Not a type of bone cancer. (12 Dec 1998) |
| spindle cell sarcoma | <tumour> A malignant neoplasm, believed to be of mesenchymal origin, composed of elongated, spindle-shaped cells. Synonym: fascicular sarcoma. (05 Mar 2000) |
| synovial sarcoma | <radiology> Soft-tissue mass, usually about 1 cm from joint, amorphous calcifications (33%), most common at knee, bone erosion (wide zone of transition), juxta-articular osteoporosis Cf: pigmented villonodular synovitis (PVS) (12 Dec 1998) |
| immunoblastic sarcoma | <tumour> Obsolete term for immunoblastic lymphoma. (05 Mar 2000) |
| osteogenic sarcoma | <oncology, tumour> A primary malignant bone cancer that arises from the cells which produce bone. It is most commonly seen in the second and third decades of life. Genetic factors appear to be important in the development of this illness. Paget's disease may be a predisposing cause. Treatment involves a combination of surgery and chemotherapy. (27 Sep 1997) |
| telangiectatic osteogenic sarcoma | <tumour> A lytic cystic variant of osteogenic sarcoma composed of aneurysmal blood-filled spaces lined by sarcoma cells producing osteoid. (05 Mar 2000) |
| endometrial stromal sarcoma | <tumour> A term sometimes used for a relatively rare sarcoma believed to be a form of endometriosis in which the lesions form multiple foci in the myometrium and in vascular spaces in other sites, and which consist of histologic and cytologic elements that resemble those of the endometrial stroma. Synonym: stromatosis. (05 Mar 2000) |
| Jensen's sarcoma | <tumour> A mouse tumour transmissible by inoculation. (05 Mar 2000) |
| ewing sarcoma | <radiology> Small, round-cell sarcoma of mesenchyme of medullary bone, age 5 - 14 yrs, most lethal of all primary bone tumours, any bone, less than 20 years of age: long bones, greater than 20 years of age: flat bones (where there's still red marrow), purely lytic (62%), purely sclerotic (15%), periosteal reaction (onion-skin or perpendicular), similar lesion at different age, less than 5 years of age -- neuroblastoma, greater than 30 years of age -- metastasis, reticulum cell sarcoma (12 Dec 1998) |