| Rous sarcoma | <tumour> A fibrosarcoma, originally observed in a Plymouth Rock hen, now thought to be an expression of infection by certain viruses of the avian leukosis-sarcoma complex in the family Retroviridae. Synonym: avian sarcoma, Rous tumour. (05 Mar 2000) |
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| Rous sarcoma virus | <virology> The virus responsible for the classic first cell free transmission of a solid tumour, the chicken sarcoma, first reported by Rous in 1911. An avian C type oncorna virus, original source of the src oncogene. (18 Nov 1997) |
| Rous sarcoma virus protease | <enzyme> Has been sequenced; crystallographic structure has been determined Registry number: EC 3.4.23.- Synonym: protease, rous sarcoma virus, rous sarcoma virus aspartic protease (26 Jun 1999) |
| Moloney murine sarcoma virus | <molecular biology, virology> Replication defective retrovirus, source of the oncogene v mos, responsible for inducing fibrosarcomas in vivo and transforming cells in culture. (18 Nov 1997) |
| moloney sarcoma virus | A replication-defective murine sarcoma virus (sarcoma viruses, murine) isolated from a rhabdomyosarcoma by moloney in 1966. (12 Dec 1998) |
| murine sarcoma virus | A seemingly defective retrovirus that produces sarcomas in mice when growing in the presence of a "helper" virus; e.g., mouse leukaemia virus. (05 Mar 2000) |
| myelogenic sarcoma | <tumour> Sarcoma originating in the bone marrow. (05 Mar 2000) |
| myeloid sarcoma | <tumour> A malignant tumour of immature myeloid cells, frequently subperiosteal, associated with or preceding granulocytic leukaemia. See: chloroma. Synonym: myeloid sarcoma. (05 Mar 2000) |
| porcine sarcoma virus | A retrovirus causing sarcoma in swine. (05 Mar 2000) |
| Harvey sarcoma virus | <oncogene> One of a family of oncogenes, first identified as transforming genes of Harvey and Kirsten murine sarcoma viruses. (Name from rat sarcoma because Harvey virus, though a mouse virus, obtained its transforming gene during passage in a rat). Transforming protein coded is p21ras, a GTP-binding protein with GTPase activity, that resembles regulatory G-proteins. (18 Nov 1997) |
| sarcoma | <oncology, tumour> A form of cancer that arises in the supportive tissues such as bone, cartilage, fat or muscle. Kaposi sarcoma: a sarcoma of spindle cells mixed with angiomatous tissue. Usually classed as an angioblastic tumour. A fairly frequent concomitant to HIV. Infection or long term immunosuppresion. (14 May 1997) |
| sarcoma, alveolar soft part | A variety of sarcoma having a reticulated fibrous stroma enclosing groups of sarcoma cells, which resemble epithelial cells and are enclosed in alveoli walled with connective tissue. It is a rare tumour, usually occurring between 15 and 35 years of age. It appears in the muscles of the extremities in adults and most commonly in the head and neck region of children. Though slow-growing, it commonly metastasizes to the lungs, brain, bones, and lymph nodes. (12 Dec 1998) |
| sarcoma, avian | Connective tissue tumours, affecting primarily fowl, that are usually caused by avian sarcoma viruses. (12 Dec 1998) |
| sarcoma botryoides | <radiology> Type of embryonal rhabdomyosarcoma, mass resembles bunch of grapes, originates submucosally, grows into lumen (12 Dec 1998) |
| sarcoma cell | Cells of a malignant tumour derived from connective tissue. Often given a prefix denoting tissue of origin, for example osteosarcoma (from bone). (18 Nov 1997) |