| GC(T)A | giant cell (temporal) arteritis |
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| GDC | giant dopamine-containing cell; General Dental Council |
| GDNF | giant cell line-derived neutrophilic factor |
| GMC | general medical clinic; general medical council; giant migratory contraction; grivet monkey cell |
| MCGC | metacerebral giant cell |
| congenital giant pigmented nevus | These large pigmented (often hairy) congenital nevi are important because of their increased risk (10 to 15%) of conversion into malignant melanoma. A biopsy can confirm if cells have turned malignant. Any change in a pre-existing nevus should prompt a physician evaluation. (27 Sep 1997) |
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| squid giant axon | <physiology> Large axons, up to 1mm in diameter, that innervate the mantle of the squid. Because of their large size, many of the pioneering investigations of the mechanisms underlying resting and action potentials in excitable cells were done on these fibres. (10 Mar 1998) |
| Langhans'-type giant cells | Multinucleated giant cell's seen in tuberculosis and other granulomas; the nuclei are arranged in an arciform manner at the periphery of the cell's. Synonym: Langhans'-type giant cells. Synonym: cytotrophoblastic cells. (05 Mar 2000) |
| acute interstitial nephritis | <nephrology> A relatively uncommon condition which is characterised by inflammation of the renal tubules, glomeruli and surrounding tissue. Interstitial nephritis is usually be temporary and often associated with the use of a particular medication. Chronic and progressive forms do exist. Drugs that have been associated with interstitial nephritis include penicillins, ampicillin, sulpha drugs, non-steroidal anti-inflammatory agents, furosemide and thiazide diuretics. May result in mild kidney dysfunction or acute renal failure. Treatment may be with corticosteroids. Incidence: 1 in 25,000. (29 Dec 1997) |
| acute interstitial pneumonitis | Usually considered a form of hypersensitivity pneumonitis. (05 Mar 2000) |
| apical interstitial lung disease | <radiology> A radiological diagnosis where fibrosis is seen in the apices (upper sections) of the lungs. Likely causes include: cystic fibrosis, ankylosing spondylitis, sarcoidosis, silicosis, eosinophlic granuloma, TB and fungus, particularly aspergillus infection. (25 Jun 1999) |
| basilar interstitial lung disease | <radiology> B bronchiectasis, A asbestosis, D drugs / DIP, L lymphangitic metastasis / LAM, A aspiration, S sarcoidosis, S scleroderma (12 Dec 1998) |
| chronic interstitial hepatitis | An obsolete term for cirrhosis of the liver. (05 Mar 2000) |
| chronic interstitial hypertrophic neuropathy | dejerine-Sottas disease |
| chronic interstitial salpingitis | Salpingitis in which fibrosis or mononuclear cell infiltration involves all layers of the fallopian or eustachian tube. Synonym: pachysalpingitis. (05 Mar 2000) |
| cystitis, interstitial | Disease that involves inflammation or irritation of the bladder wall. This inflammation can lead to scarring and stiffening of the bladder, and even ulcerations and bleeding. Diagnosis is based on symptoms, findings on cystoscopy and biopsy, and eliminating other treatable causes such as infection. Because doctors do not know what causes IC, treatments are aimed at relieving symptoms. most people are helped for variable periods of time by one or a combination of treatments. (12 Dec 1998) |
| hypertrophic interstitial neuropathy | Sensorimotor neuropathy characterised pathologically by collections of Schwann cell processes arranged concentrically around one or more nerve fibres. No genetic factors are known in its aetiology.For hereditary types, see hereditary hypertrophic neuropathy. (05 Mar 2000) |
| nephritis, interstitial | Primary or secondary disease of the renal interstitial tissue resulting from arterial, arteriolar, glomerular, or tubular disease which destroys individual nephrons, or from toxic involvement of interstitital cells and tubules due to systemic diseases such as gout, to drug exposure, or to mercury poisoning. Clinically it may be manifested primarily by loss of concentrating capacity, mineral wasting, proteinuria, and abnormal urine sediment. It may be seen in an acute form, particularly after specific bacterial infection, and may result in acute papillary necrosis. More commonly, the process is a chronic one with progressive renal atrophy and diminution of renal function. (12 Dec 1998) |
| diffuse interstitial fibrosis | Progressive fibrous changes and scarring within the lung tissue, eventually interfering with normal gas exchange. (27 Sep 1997) |
| diffuse interstitial pulmonary fibrosis | This represents a group of pulmonary disorders (lower respiratory tract) that leads to a functional loss in the alveolar air sacs and a compromise in the diffusion of oxygen from air to blood. There is widespread inflammation and scar tissue (fibrosis) formation within the lung. The causes are varied and include: inorganic and organic dusts, gases, fumes, vapors, infections, radiation, medications, coal dust, silicosis and byssinosis. When the cause is not identifiable it is referred to as idiopathic diffuse interstitial pulmonary fibrosis (27 Sep 1997) |