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ochratoxin A hydroxylase <enzyme> Catalyzed by the cytochrome p450ia1 isoenzyme
Registry number: EC 1.14.99.-
Synonym: ochratoxin 4-hydroxylase
(26 Jun 1999)
taurochenodeoxycholic acid 6alpha-hydroxylase <enzyme> A 53 kD hydroxylase from pig liver microsomes which forms hyocholic acid (3alpha,6alpha,7alpha-trihydroxy-5beta-cholanoic acid; member of the cyp 4a family; n-terminal amino acid sequence given in first source
Registry number: EC 1.14.99.-
Synonym: tcdca 6alpha-hydroxylase
(26 Jun 1999)
testosterone 15-alpha hydroxylase <enzyme> A haem-thiolate protein (cytochrome p-450)
Registry number: EC 1.14.15.-
Synonym: cytochrome p-450(15alpha), testosterone 15-alpha monooxygenase, steroid 15-alpha-hydroxylase, cytochrome p-4502a-4, cyp2a-4, cyp2a4
(26 Jun 1999)
testosterone 16 beta-hydroxylase <enzyme> See also record for testosterone hydroxylase
Registry number: EC 1.14.99.-
Synonym: ttt 16 beta-hydroxylase
(26 Jun 1999)
testosterone 2alpha-hydroxylase <enzyme> From mouse liver, member of the murine cytochrome p450 2d family; amino-terminal amino acid sequence given in first source
Registry number: EC 1.14.99.-
Synonym: cytochrome p450 2alpha, cytochrome p-450 2alpha, androstenedione 2alpha-hydroxylase, androgen 2alpha-hydroxylase
(26 Jun 1999)
testosterone 6-beta hydroxylase <enzyme> Pcn2 is an allelic variant form (2 amino acid alterations); for cyp3a2, consider also lidocaine n-deethylase
Registry number: EC 1.14.13.-
Synonym: cytochrome p450(6 beta), cytochrome p-450 6b-1(pb1), cyp6b1, testosterone 6beta-hydroxylase, cyt p450 6beta-3, cytochrome p450(pcn2), 6beta-a gene product, cyp3a2, cyp6b3
(26 Jun 1999)
testosterone hydroxylase <enzyme> Acts at positions 6 alpha, 7 alpha and 16 alpha; see also records for testosterone 16 beta-hydroxylase and testosterone 6 beta-hydroxylase
Registry number: EC 1.14.-
Synonym: testosterone 16 alpha-hydroxylase, testosterone 7 alpha-hydroxylase
(26 Jun 1999)
ecdysteroid 26-hydroxylase <enzyme> Converts ecdysone to 26-hydroxyecdysone in the presence of NADPH
Registry number: EC 1.14.13.-
(26 Jun 1999)
tolbutamide 4-hydroxylase <enzyme> Several isoenzymes of cytochrome p-450 catalyze this reaction, including cyp2c8, cyp2c9 and cyp2c10
Registry number: EC 1.14.99.-
Synonym: phenytoin hydroxylase
(26 Jun 1999)
ent-kaurenoic acid 13-hydroxylase <enzyme> Forms steviol (ent-kaur-16-en-13-ol-19-oic acid) using NADPH and o2; n-terminal amino acid sequence given in first source
Registry number: EC 1.14.13.-
Synonym: ent-ka 13-hydroxylase
(26 Jun 1999)
erythromycin C-12 hydroxylase <enzyme> Required for the c-12 hydroxylation of the macrolactone ring in erythromycin synthesis; mw 44 kD; from saccharopolyspora erythraea; amino acid sequence given in first source
Registry number: EC 1.14.-
Synonym: hydroxylase eryk, eryk gene product, cytochrome p-450(eryk)
(26 Jun 1999)
tryptophan hydroxylase <enzyme> An enzyme that catalyses the hydroxylation of tryptophan to 5-hydroxytryptophan in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of serotonin.
Chemical name: L-tryptophan,tetrahydropteridine:oxygen oxidoreductase (5-hydroxylating)
Registry number: EC 1.14.16.4
(12 Dec 1998)
estradiol 15 alpha-hydroxylase <enzyme> Catalyses the conversion of estradiol to 15alpha-hydroxyestradiol
Registry number: EC 1.14.99.-
Synonym: e15a-hydroxylase
(26 Jun 1999)
estradiol 16 alpha-hydroxylase <enzyme> Cyp2c11 is a male-specific cyp isoform
Registry number: EC 1.14.99.-
Synonym: 16 alpha-hydroxylase, estrone 16 alpha-hydroxylase, 16alpha-hydroxylase, steroid 16 alpha-hydroxylase, estrone 3-sulfate 16 alpha-hydroxylase, cytochrome p450cmf, cytochrome p450 2c, cytochrome p450iic11, cytochrome p450(ut-a), cytochrome p4502c-rml5, cytochrome p450h, cytochrome p450(male), cytochrome p4502c, cytochrome p450 2c3, cytochrome p450 2c9, oestrogen 16-hydroxylase, cyp2c3 gene product, cyp2c11 gene product, cytochrome p450 2c11, cyp 2d-9, cytochrome p450(tb), cyp2c9, cytochrome p-450(m1), cyp2c11
(26 Jun 1999)
estrogen 2-hydroxylase <enzyme> Same enzyme for hydroxylation in 2 or 4 position
Registry number: EC 1.14.99.-
Synonym: estrogen 4-hydroxylase, ethinylestradiol 2-hydroxylase
(26 Jun 1999)
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