| 2-hydroxy-4-carboxymucconate-6-saemialdehyde dehydrogenase | <enzyme> Catalyses alpha-hydroxy-gamma-carboxymuconic-epsilon-saemialdehyde to alpha-hydroxy-gamma-carboxymuconic acid Registry number: EC 1.2.1.45 Synonym: alpha-hydroxy-gamma-carboxymuconic-epsilon-saemialdehyde dehydrogenase, chms dehydrogenase (26 Jun 1999) |
|---|---|
| 2-hydroxy-5-nitrobenzyl bromide | <chemical> 2-(bromomethyl)-5-nitrophenol. A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as koshland's reagent. Pharmacological action: indicators and reagents. Chemical name: Phenol, 2-(bromomethyl)-4-nitro- (12 Dec 1998) |
| 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase | <enzyme> Above cpd hydrolyzed to 2-oxopent-4-enoate (2-hydroxypenta-2,4-dienoate); enzyme e of p-cumate catabolic pathway in pseudomonas putida Registry number: EC 3.7.- Synonym: hodh hydrolase, 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase, cmte gene product (26 Jun 1999) |
| 2-hydroxy-isonicotinic acid hydroxylase | <enzyme> Forms 2,6-dihydroxy-isonicotinic acid (citrazinic acid); contains iron and a flavin; incorporates hydroxyl group of water Registry number: EC 1.- Synonym: hinah (26 Jun 1999) |
| 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | <enzyme> E coli enzyme; catalyses formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate from 2-ketoglutarate and isochorismate; requires thiamine pyrophosphate and liberates pyruvate from the isochorismate molecule; see also o-succinylbenzoate synthase Registry number: EC 4.1.3.- Synonym: shchc synthase (26 Jun 1999) |
| 3a-hydroxy-5a-pregnan-20-one | A catabolite of progesterone; found in the urine of pregnant women. (05 Mar 2000) |
| 3 beta-hydroxy-delta 5-C(27)-steroid dehydrogenase | <enzyme> Second enzyme in the sequence that converts cholesterol to bile acids; deficiency leads to chronic liver disease in childhood Registry number: EC 1.1.1.- Synonym: 7 alpha-hydroxycholesterol 3 beta-dehydrogenase, 7-hydroxycholesterol 3-dehydrogenase, 3 beta-hydroxy-delta(5)-c(27)-steroid oxidoreductase, 5-cholestene-3beta,7alpha-diol oxidase (26 Jun 1999) |
| 3-hydroxy-2-methylpropionyl-CoA dehydrogenase | <enzyme> Forms methylmalonyl-CoA saemialdehyde Registry number: EC 1.1.1.- Synonym: 3-hydroxyisobutyryl-CoA dehydrogenase (26 Jun 1999) |
| 3-hydroxy-2-pyrrolidinecarboxylic acid | A derivative of proline found in certain collagens, particularly basement membrane collagen. Synonym: 3-hydroxy-2-pyrrolidinecarboxylic acid. (05 Mar 2000) |
| 3-hydroxy-3-methylglutaryl-CoA | -OOCCH2C(OH)(CH3)CH2COS-CoA;a key intermediate in the synthesis of ketone bodies and of steroids. Synonym: 3-hydroxy-3-methylglutaryl-CoA. Beta-hydroxy-beta-methylglutaryl-lyase, an enzyme, found primarily in liver and rumen epithelium that catalyses the formation of acetyl-CoA and acetoacetate from beta-hydroxy-beta-methylglutaryl-CoA; a key step in ketogenesis; a deficiency of this enzyme leads to episodes of severe metabolic acidosis without ketosis. Beta-hydroxy-beta-methylglutaryl-reductase, an enzyme that catalyses the rate-limiting step of cholesterol biosynthesis, beta-hydroxy-beta-methylglutaryl-CoA + 2NADPH + 2H+ → mevalonate + 2NADP+ + coenzyme A. Beta-hydroxy-beta-methylglutaryl-synthase, an enzyme in mitochondria that catalyses the reaction of acetyl-CoA with acetoacetyl-CoA and water to form beta-hydroxy-beta-methylglutaryl-CoA and coenzyme A, a step required for both ketogenesis and steroidogenesis to occur. (05 Mar 2000) |
| 3-hydroxy-4-oxoquinoline oxygenase | <enzyme> Forms n-formylanthranilic acid + co2; 24 amino acids of n-terminal sequence given in first source Registry number: EC 1.13.12.- Synonym: 1h-3-hydroxy-4-oxoquinoline oxygenase, 3-oh-4-oxoquinoline oxygenase (26 Jun 1999) |
| 4-(4'-hydroxy-3'-methylbut-2'-enyl)-L-tryptophan synthetase | <enzyme> Enzymatic synthesis of above cpd from isopentenylpyrophosphate and tryptophan Registry number: EC 6.- (26 Jun 1999) |
| 4-hydroxy-2-ketopimelate aldolase | <enzyme> Bacterial enzyme functioning in pathways of aromatic catabolism; forms pyruvate and succinic saemialdehyde Registry number: EC 4.1.3.- (26 Jun 1999) |
| 4-hydroxy-2-ketovalerate aldolase | <enzyme> Forms acetaldehyde + pyruvate; catalyses conversion of 4-hydroxy-2-ketovalerate to pyruvate Registry number: EC 4.1.3.- (26 Jun 1999) |
| 4-hydroxy-2-oxovalerate aldolase | <enzyme> Forms pyruvate + acetaldehyde; enzyme g of p-cumate catabolic pathway in pseudomonas putida Registry number: EC 4.1.3.- Synonym: nahm gene product, cmtg gene product (26 Jun 1999) |