| ichthyosis simplex | most common form of ichthyosis characterised by prominent scaling especially on the exterior surfaces of the extremities. It is inherited as an autosomal dominant trait. (12 Dec 1998) |
|---|---|
| epidermolysis bullosa simplex | This represents a group of rare inherited disorders in which blistering of the skin occurs in response to skin trauma. Large fluid-filled blisters can occur in response to injury, skin rubbing, chafing or even increases in room temperature. Secondary bacterial infection of the blisters is common. Complications include oesophageal stricture, infections, loss of function of hands and feet and malnutrition. The dermatologist is the expert in the evaluation and treatment of this disorder. (27 Sep 1997) |
| erythema simplex | Blushing or redness of the skin caused by a toxic reaction or a neurovascular phenomenon. Synonym: dermatitis simplex. (05 Mar 2000) |
| lichen simplex chronicus | A thickened area of itching skin resulting from rubbing and scratching. (05 Mar 2000) |
| lobulus simplex | The smaller anterior part of the posterior lobe of the cerebellum, demarcated by the primary fissure from the anterior lobe rostrally and from the large caudal subdivision of the posterior lobe caudally. Synonym: lobulus simplex. (05 Mar 2000) |
| lymphangioma simplex | A circumscribed region or focus of several to numerous lymphatic vessels that are moderately dilated. Synonym: simple lymphangiectasis. (05 Mar 2000) |
| lymphangioma superficium simplex | A congenital nevoid lesion consisting of a circumscribed group of tense lymph vesicles. Synonym: lupus lymphaticus, lymphangiectodes, lymphangioma capillare varicosum, lymphangioma superficium simplex. (05 Mar 2000) |
| bacteriophage T3 RNA polymerase | <enzyme> Used for the rapid generation of strand-specific RNA molecules that can be used for the identification of genes in hybridization experiments Registry number: EC 2.7.7.- Synonym: t3 RNA polymerase (26 Jun 1999) |
| ribonucleotide polymerase | <enzyme> DNA-dependent Registry number: EC 2.7.7.- Synonym: oligonucleotide polymerase, decaribonucleotide polymerase (26 Jun 1999) |
| ribose polymerase | <enzyme> Enzyme that catalyses the attachment of ADP ribose units to various nuclear proteins. This post translational modification of proteins is dependent on DNA and appears to be involved in the regulation of various cellular processes such as differentiation, proliferation and transformation. (18 Nov 1997) |
| RNA polymerase | <enzyme, molecular biology> An enzyme that polymerise ribonucleotides in accordance with the information present in DNA. Prokaryotes have a single enzyme for the three RNA types that is subject to stringent regulatory mechanisms. Eukaryotes have type I that synthesises all rRNA except the 5S component, type II that synthesises mRNA and hnRNA and type III that synthesises tRNA and the 5S component of rRNA. (23 Aug 1998) |
| RNA polymerase I | <enzyme> A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. The enzyme functions in the nucleolar structure and transcribes DNA into RNA. It has different requirements for cations and salts than RNA polymerase II and III and is not inhibited by alpha-amanitin. Registry number: EC 2.7.7.- (12 Dec 1998) |
| RNA polymerase II | <enzyme> A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure and transcribes DNA into RNA. It has different requirements for cations and salt than RNA polymerase I and is strongly inhibited by alpha-amanitin. Registry number: EC 2.7.7.- (12 Dec 1998) |
| RNA polymerase III | <enzyme> A DNA-dependent RNA polymerase present in bacterial, plant, and animal cells. It functions in the nucleoplasmic structure where it transcribes DNA into RNA. It has specific requirements for cations and salt and has shown an intermediate sensitivity to alpha-amanitin in comparison to RNA polymerase I and II. Registry number: EC 2.7.7.- (12 Dec 1998) |
| MS2 polymerase | <enzyme> Used in formation of fusion proteins Registry number: EC 2.7.7.- (26 Jun 1999) |