| foreign body giant cell | <pathology> Syncytium formed by the fusion of macrophages in response to an indigestible particle too large to be phagocytosed for example talc, silica or asbestos fibres). There may be as many as 100 nuclei randomly distributed: similar cells but with the nuclei more peripherally located (Langhans cells) are found at the centre of tuberculous lesions. (06 Mar 1998) |
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| acute decubitus ulcer | A severe form of bedsore, of neutrophic origin, occurring in hemiplegia or paraplegia. (05 Mar 2000) |
| Aden ulcer | The lesion occurring in cutaneous leishmaniasis. (05 Mar 2000) |
| amputating ulcer | An ulcer encircling a limb. (05 Mar 2000) |
| anastomotic ulcer | An ulcer of jejunum, after gastroenterostomy. (05 Mar 2000) |
| anti-ulcer agents | Various agents with different action mechanisms used to treat or ameliorate ulcers or irritation of the gastrointestinal tract. (12 Dec 1998) |
| aphthous ulcer | <gastroenterology> A type of benign mouth ulcer often caused by injury to the mucosal lining of the oral cavity, viral infection or vitamin deficiency. (27 Sep 1997) |
| atonic ulcer | An ulcer that shows little or no tendency to heal. (05 Mar 2000) |
| Buruli ulcer | An ulcer of the skin, with widespread necrosis of subcutaneous fat, due to infection with Mycobacterium ulcerans; occurs in Uganda in persons living on the Nile river banks. Origin: Buruli, district in Uganda (05 Mar 2000) |
| Gaboon ulcer | A form of tropical ulcer affecting the residents of this region; it resembles a syphilitic ulcer, especially in the appearance of its scar. Origin: Gaboon, a region in Africa (05 Mar 2000) |
| varicose ulcer | Ulcer due to varicose veins. Chronic venous insufficiency in the deep veins of the legs leads to shunting the venous return into the superficial veins, in which pressure and flow rate, as well as oxygen content, are increased. (12 Dec 1998) |
| gastric ulcer | <gastroenterology> An ulcer in the mucosal lining of the stomach. Ulcer formation results from gastric inflammation that may be triggered by the use of alcohol, aspirin or non-steroidal anti-inflammatories agents. Symptoms include recurrent abdominal pains (may be relieved by antacids), nausea, vomiting, weight loss and fatigue. Complications include GI bleeding, obstruction, perforation and ulcer penetration into surrounding tissues. Treatment includes the avoidance of alcohol, smoking, aspirin, anti-inflammatories and caffeine. Medications such as antacids or H2 antagonists (for example cimetidine, ranitidine) or proton pump inhibitors (omeprazole) have been shown to be effective treatment. (27 Sep 1997) |
| Mann-Williamson ulcer | <surgery> An operation performed on experimental animals (dogs) in research on peptic ulcer, the duodenum with its alkaline secretions being transplanted into the ileum and the cut end of the jejunum anastomosed to the pylorus. The animals develop ulcers in the jejunum which directly receives the gastric juice. (05 Mar 2000) |
| venereal ulcer | A sexually transmitted disease caused by the bacteria haemophilus ducreyi. Causes multiple painful ulcers on the penis and the vulva often associated with tender and enlarged inguinal lymph nodes. (27 Sep 1997) |
| marginal ring ulcer of cornea | A slowly advancing intermittent ulcer involving the circumference of the corneal margin. (05 Mar 2000) |