| CR | calculation rate; calculus removed; calorie-restricted; cardiac rehabilitation; cardiac resuscitatio... |
|---|---|
| CRL | cell repository line; Certified Record Librarian; complement receptor location; complement receptor ... |
| DR | degeneration reaction; delivery room; deoxyribose; diabetic retinopathy; diagnostic radiology; digit... |
| ERA | electrical response activity; electroencephalic response audiometry; Electroshock Research Associati... |
| ERP | early receptor potential; effective refractory period; elodoisin-related peptide; endoscopic retrogr... |
| genes, overlapping | Genes whose nucleotide sequences overlap to some degree. The overlapped sequences may involve structural or regulatory genes of eukaryotic or prokaryotic cells. (12 Dec 1998) |
|---|---|
| genes, p16 | Tumour suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (12 Dec 1998) |
| genes, p53 | Tumour suppressor genes located on the short arm of human chromosome 17 and coding for the phosphoprotein p53. (12 Dec 1998) |
| genes, plant | The hereditary material of plants. (12 Dec 1998) |
| genes, pol | DNA sequences that form the coding region for retroviral enzymes including reverse transcriptase, protease, and endonuclease/integrase. "pol" is short for polymerase, the enzyme class of reverse transcriptase. (12 Dec 1998) |
| genes, protozoan | The genetic material of protozoa. (12 Dec 1998) |
| genes, px | DNA sequences that form the coding region for at least three proteins which regulate the expression of HTLV-I and HTLV-II. The proteins are p21(x), p27(rex), and p40(tax). The tax (trans-activator x) and rex (regulator x) genes are part of px but are in overlapping reading frames. X was the original designation for the sequences or region (at that time of unknown function) in the long open reading frame (lor) which is now called px. (12 Dec 1998) |
| genes, rag-1 | Genes involved in activating the enzyme vdj recombinase. Rag-1 is located on chromosome 11 in humans (chromosome 2 in mice) and is expressed exclusively in maturing lymphocytes. (12 Dec 1998) |
| genes, ras | Family of retrovirus-associated DNA sequences (ras) originally isolated from harvey (h-ras, ha-ras, rash) and kirsten (k-ras, ki-ras, rask) murine sarcoma viruses. Ras genes are widely conserved among animal species and sequences corresponding to both h-ras and k-ras genes have been detected in human, avian, murine, and non-vertebrate genomes. The closely related n-ras gene has been detected in human neuroblastoma and sarcoma cell lines. All genes of the family have a similar exon-intron structure and each encodes a p21 protein. (12 Dec 1998) |
| genes, recessive | Genes that are reflected in the phenotype only in the homozygous state. (12 Dec 1998) |
| genes, regulator | Genes which regulate or circumscribe the activity of other genes; specifically, genes which code for proteins (repressors or activators) which regulate the genetic transcription of the structural genes and/or regulatory genes. (12 Dec 1998) |
| genes, reporter | Genes whose expression is easily detectable and therefore used to study promoter activity at many positions in a target genome. In recombinant DNA technology, these genes may be attached to a promoter region of interest. (12 Dec 1998) |
| genes, retinoblastoma | Tumour suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kD to 115 kD. One copy of the wild-type rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma. (12 Dec 1998) |
| genes, rev | DNA sequences that form the coding region for a protein that regulates the expression of the viral structural and regulatory proteins in human immunodeficiency virus (HIV). Rev is short for regulator of virion. (12 Dec 1998) |
| genes, src | Retrovirus-associated DNA sequences (src) originally isolated from the rous sarcoma virus (rsv). The proto-oncogene src (c-src) codes for a protein that is a member of the tyrosine kinase family and was the first proto-oncogene identified in the human genome. The human c-src gene is located at 20q12-13 on the long arm of chromosome 20. (12 Dec 1998) |