| gene rearrangement, t-lymphocyte | Ordered rearrangement of T-cell variable gene regions coding for the antigen receptors. (12 Dec 1998) |
|---|---|
| gene redundancy | A situation in which many copies of the same gene exist in a genome. (09 Oct 1997) |
| gene regulation | The DNA and protein interactions in a gene that determine the temporal and spatial modes of expression as well as the amplitude of expression. (14 Nov 1997) |
| gene regulatory protein | <molecular biology> Any protein that interacts with DNA sequences of a gene and controls its transcription. (18 Nov 1997) |
| gene sequencing | Determination of the sequence of nucleotide bases in a strand of DNA. (14 Nov 1997) |
| gene splicing | A procedure by which one DNA molecule or fragment can be attached to another. (14 Nov 1997) |
| gene supression | <molecular biology> The halting of abnormal gene activity which results in the restoration of lost or impaired genetic function. (09 Oct 1997) |
| gene switch | <molecular biology> A situation in which a cell or organism stops expressing one gene orgene group and switches to expressing a different gene or group of genes. (09 Oct 1997) |
| gene synthesis | <molecular biology> The complete synthesis of a gene using a DNA synthesiser (gene machine), or the assembly of oligonucleotides so synthesised into a synthetic gene, as opposed to cloning. (14 Nov 1997) |
| gene targeting | The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination. (12 Dec 1998) |
| gene testing | Testing a sample of blood (or another fluid or tissue) for evidence of a gene. The evidence can be biochemical, chromosomal, or genetic. The aim is to learn whether a gene for a disease is present or absent. (12 Dec 1998) |
| gene therapy | <molecular biology> Treatment of a disease caused by malfunction of a gene, by stably transfecting the cells of the organism with the normal gene. (18 Nov 1997) |
| gene transfer | <molecular biology> General tem for the insertion of foreign genes into a cell or organism. Synonymous with transfection. (18 Nov 1997) |
| gene translocation | The movement of a gene fragment from one chromosomal location to another, which often alters or abolishes expression. (09 Oct 1997) |
| gene, evolutionarily conserved | A gene that has remained essentially unchanged throughout evolution. Conservation of a gene indicates that it is unique and essential. There is not an extra copy of that gene with which evolution can tinker. And changes in the gene are likely to be lethal. (12 Dec 1998) |
| hox gene | <molecular biology> Homeobox containing genes of vertebrates. (18 Nov 1997) |
|---|---|
| human gene therapy | <molecular biology, technique> Insertion of normal DNA directly into cells to correct a genetic defect. (09 Oct 1997) |
| HuP gene | <molecular biology> Human equivalents of the Pax genes. (18 Nov 1997) |
| S gene complex | <molecular biology> Genes coding for molecular components of the pollen stigma recognition system in the cabbage genus Brassica). The gene products govern the self incompatibility response and include a glycoprotein found on the stigma surface and a lectin on the pollen grain surface that binds to the stigma glycoprotein. (18 Nov 1997) |
| single-gene diseases | Hereditary disorders caused by a change (mutation) in a single gene. There are thousands of single-gene diseases including achondroplastic dwarfism, huntington disease, cystic fibrosis, sickle cell disease, duchenne muscular dystrophy, and haemophilia. Single-gene diseases typically describe classic simple mendelian patterns of inheritance (as autosomal dominant, autosomal recessive, and x-linked traits) by comparison with polygenic diseases. (12 Dec 1998) |
| single gene disorder | Hereditary disorder caused by a mutant allele of a single gene (for example, Duchenne muscular dystrophy, retinoblastoma, sickle cell disease). Compare: polygenic disorders. (09 Oct 1997) |
| somatic cell gene therapy | The repair or replacement of a defective gene within somatic tissue. (09 Oct 1997) |
| split gene | Non-coding, intervening sequences of DNA that are transcribed, but are removed from within the primary gene transcript and rapidly degraded during maturation of messenger RNA. most genes in the nuclei of eukaryotes contain introns, as do mitochondrial and chloroplast genes. (12 Dec 1998) |
| neurogenic gene | Best described in Drosophila, genes that are required to determine a neuronal fate. Examples: Notch, Delta. (18 Nov 1997) |
| structural gene | A gene that codes for a product (e.g. An enzyme, structural protein, tRNA), as opposed to a gene that serves a regulatory role. (18 Nov 1997) |
| nif gene | <molecular biology> The complex of genes in nitrogen fixing bacteria that code for the proteins required for nitrogen fixation, particularly the nitrogenase. Present as an operon in Klebsiella and carried on plasmid in Rhizobium which inhabit the roots of leguminous plants. (13 Nov 1997) |
| d4dr gene | <molecular biology> A gene which regulates a protein that plays a role in transmitting messages carried by dopamine between neurons (brain cells). A particular form of the gene may have an affect on an individual's personality since it seems to occur in individuals with novelty-seeking behaviour. (09 Oct 1997) |
| dam gene | <molecular biology> A gene that codes for the synthesis of a DNA adenine methylase. (09 Oct 1997) |
| supressor gene | <molecular biology> A gene that can reverse the effect of a mutation in other genes. (14 Nov 1997) |
| syntenic gene | <molecular biology> Genes that are believed to belocated on the same chromosome because they are lost along with a marker gene that is known to be located on that chromosome. (19 Jan 1998) |
Synonyms : Fusion, Gene, Fusions, Gene, Gene Fusions
Synonyms : DNA Libraries, Gene Libraries, Libraries, DNA, Libraries, Gene, Libraries, cDNA, Library, DNA, Library, Gene, Library, cDNA, cDNA Libraries
Synonyms : Gene Arrangement, Gene Position, Arrangement, Gene, Arrangements, Gene, Gene Arrangements, Gene Positions, Order, Gene, Position, Gene, Positions, Gene
Synonyms : Gene Pools, Pool, Gene, Pools, Gene
Synonyms : env Antigens, env Glycoproteins, env Polyprotein, Antigens, env, Glycoproteins, env, Polyprotein, env, Polyproteins, env, Products, env Gene, Protein, env
| generalist |
Renaissance man: a modern scholar who is in a position to acquire more than superficial knowledge about many different interests; "a statistician has to be something of a generalist"
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|---|---|
| generalized anxiety disorder |
an anxiety disorder characterized by chronic free-floating anxiety and such symptoms as tension or sweating or trembling of lightheadedness or irritability etc that has lasted for more than six months
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| generalized |
not biologically differentiated or adapted to a specific function or environment; "the hedgehog is a primitive and generalized mammal" spread throughout a body or system; "generalized edema"
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| generation |
coevals: all the people living at the same time or of approximately the same age group of genetically related organisms constituting a single step in the line of descent the normal time between successive generations; "they had to wait a generation for that prejudice to fade" a stage of technological development or innovation; "the third generation of computers" genesis: a coming into being the production of heat or electricity; "dams were built for the generation of electricity" the act of producing offspring or multiplying by such production
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| generalized epilepsy |
grand mal epilepsy: epilepsy in which the attack involves loss of consciousness and tonic spasms of the musculature followed by generalized jerking
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| gene | military officers assigned to assist a senior officer in planning military policy |
|---|---|
| gene | a retail store serving a sparsely populated region |
| gene | a generalization of special relativity to include gravity (based on the principle of equivalence) |
| gene | an ordinary verdict declaring which party prevails without any special findings of fact |
| gene | not limited in use or function |
| gene | (psychology) transfer of a response learned to one stimulus to a similar stimulus |
| gene | reasoning from detailed facts to general principles |
| gene | the process of formulating general concepts by abstracting common properties of instances |
| gene | an idea having general application |
| gene | become systemic |
| gene | cater to popular taste to make popular and present to the general public |
| gene | draw from specific cases for more general cases |
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