| gastrin | <hormone, protein> A group of peptide hormones secreted by the mucosal gut lining of some mammals in response to mechanical stress or high pH. When there is food in the stomach, these cells secrete gastrin. Gastrin then stimulates the stomach parietal cells to produce hydrochloric acid. Normally, as stomach pH lowers, gastrin secretion decreases. Gastrin blood levels can be determined to be elevated in conditions such as Zollinger-Ellison syndrome and pernicious anaemia. Several different gastrins have been identified, human gastrin I has 16 amino acids (2116 D). Gastrin is competitively inhibited by cholecystokinin. (05 Jan 1998) |
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| gastrin-releasing peptide | <hormone> A regulatory peptide (27 amino acids) thought to be the mammalian equivalent of bombesin. It elicits gastrin release and regulates gastric acid secretion and motor function. It causes bronchoconstriction and vasodilation in the respiratory tract and stimulates the growth and mitogenesis of cells in culture. Once released from nerves in the antrum of the stomach, the neuropeptide stimulates release of gastrin from the g cells. Chemical name: Gastrin-releasing peptide (12 Dec 1998) |
| gastrinase | <enzyme> Highly specific for the 34 amino acid gastrin Registry number: EC 3.4.99.- Synonym: gastrin-34 protease, gastrin-34 degrading enzyme (26 Jun 1999) |
| gastrinoma | <oncology, tumour> A tumour (gastrinoma) of the pancreatic islet cells that results in an over production of gastric acid, leading to fulminant ulceration of the oesophagus, stomach, duodenum and jejunum. Gastrinomas may also occur in the stomach, duodenum, spleen and regional lymph nodes. Treatment includes the use of H2 antagonists (for example cimetidine, ranitidine). Surgical excision of the tumour is curative in approximately 25% of patients. (27 Sep 1997) |
| gastrins | A family of gastrointestinal peptide hormones that excite the secretion of gastric juices. They may also occur in the central nervous system where they are presumed to be neurotransmitters. (12 Dec 1998) |
| gastritis | <pathology> Inflammation of the stomach. (18 Nov 1997) |
| gastritis cystica polyposa | Large sessile mucosal polyps arising in the stomach proximal to an old gastroenterostomy. (05 Mar 2000) |
| gastritis fibroplastica | An obsolete term for gastritis with fibrosis and sclerosis. (05 Mar 2000) |
| gastritis, atrophic | Chronic gastritis with mucosal atrophy. (12 Dec 1998) |
| gastritis, hypertrophic | Gastritis with hypertrophy of gastric mucosa folds. Symptoms include vomiting, diarrhoea, weight loss, excessive mucus secretion, and hypoproteinaemia. (12 Dec 1998) |
Synonyms : Gastrin
Synonyms : Gastritides
Synonyms : Atrophic Gastritides, Atrophic Gastritis, Gastritides, Atrophic
Synonyms : Giant Hypertrophic Gastritis, Disease, Menetrier, Gastritis, Giant Hypertrophic, Hypertrophic Gastritis, Hypertrophic Gastritis, Giant
| gastric atrophy |
A condition in which the stomach muscles shrink and become weak. The digestive (peptic) glands may also shrink, resulting in a lack of digestive juices.
Ãâó: www.stjude.org/glossary
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| gastric reflux |
The backward flow of stomach acid contents into the esophagus (the tube that connects the mouth to the stomach). Also called esophageal reflux or gastroesophageal reflux.
Ãâó: www.stjude.org/glossary
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| gastric juice |
digestive fluids produced by the lining of the stomach that break down proteins and destroy harmful organisms
Ãâó: www.american-depot.com/services/resources_gl_g.asp
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| gastric lavage |
washing out of the stomach with water, often to treat poisoning; commonly called "stomach pumping"
Ãâó: www.american-depot.com/services/resources_gl_g.asp
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| gastritis |
inflammation of the mucous membrane lining of the stomach; can have a number of causes, including viruses, bacteria, and use of alcohol and other drugs
Ãâó: www.american-depot.com/services/resources_gl_g.asp
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