| giant hives | A vascular reaction involving the deep dermis or subcutaneous or submucal tissues, representing localised oedema caused by dilatation and increased permeability of the capillaries and characterised by development of giant wheals. (18 Nov 1997) |
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| giant hypertrophy of gastric mucosa | Gastric mucosal hyperplasia, either mucoid or glandular; the latter type may be associated with the Zollinger-Ellison syndrome. Synonym: giant hypertrophy of gastric mucosa, hypertrophic gastritis, Menetrier's syndrome. (05 Mar 2000) |
| giant lymph node hyperplasia | Large benign, hyperplastic lymph nodes. The more common hyaline vascular subtype is characterised by small hyaline vascular follicles and interfollicular capillary proliferations. Plasma cells are often present and represent another subtype with the plasma cells containing IgM and IgA. (12 Dec 1998) |
| giant melanosome | A large spherical melanosome (1 to 6 u in diameter) formed in the cytoplasm of melanocytes in cafe-au-lait spots and other melanocytic disorders. Synonym: macromelanosome. (05 Mar 2000) |
| giant osteoid osteoma | A benign, painful, tumour of bone characterised by the formation of osteoid tissue, primitive bone and calcified tissue. It occurs frequently in the spine of young persons. (12 Dec 1998) |
| giant pigmented nevus | These large pigmented (often hairy) congenital nevi are important because of their increased risk (10 to 15%) of conversion into malignant melanoma. A biopsy can confirm if cells have turned malignant. Any change in a pre-existing nevus should prompt a physician evaluation. (27 Sep 1997) |
| giant urticaria | A vascular reaction involving the deep dermis or subcutaneous or submucal tissues, representing localised oedema caused by dilatation and increased permeability of the capillaries and characterised by development of giant wheals. (18 Nov 1997) |
| congenital giant pigmented nevus | These large pigmented (often hairy) congenital nevi are important because of their increased risk (10 to 15%) of conversion into malignant melanoma. A biopsy can confirm if cells have turned malignant. Any change in a pre-existing nevus should prompt a physician evaluation. (27 Sep 1997) |
| squid giant axon | <physiology> Large axons, up to 1mm in diameter, that innervate the mantle of the squid. Because of their large size, many of the pioneering investigations of the mechanisms underlying resting and action potentials in excitable cells were done on these fibres. (10 Mar 1998) |
| Langhans'-type giant cells | Multinucleated giant cell's seen in tuberculosis and other granulomas; the nuclei are arranged in an arciform manner at the periphery of the cell's. Synonym: Langhans'-type giant cells. Synonym: cytotrophoblastic cells. (05 Mar 2000) |
| T-cell-rich, B-cell lymphoma | <tumour> A B-cell lymphoma in which more than 90% of the cells are of T-cell origin, masking the large cells that form the neoplastic B-cell component. See: adult T-cell lymphoma. (05 Mar 2000) |
| acetone body | <biochemistry> Any of the three compounds created by acetyl coenzyme A (acetoacetate, hydroxybutyrate, and acetone) which are water-soluble cellular fuels normally exported by the liver. They can build up in the blood and body tissues because of starvation, untreated diabetes mellitus, or other disorders that interfere with carbohydrate metabolism. The body rids itself of ketones mainly through urine, but it rids itself of acetone through the lungs, which gives the breath a characteristic fruity odour. If ketones build up in the body long enough, they cause serious illness and coma (see ketoacidosis.) (09 Oct 1997) |
| acute inclusion body encephalitis | The most common acute encephalitis, caused by HSV-1; affects persons of any age; preferentially involves the inferomedial portions of the temporal lobe and the orbital portions of the frontal lobes; pathologically, severe haemorrhagic necrosis is present along with, in the acute stages, intranuclear eosinophilic inclusion bodies in the neurons and glial cells. Synonym: acute inclusion body encephalitis, herpes encephalitis. (05 Mar 2000) |
| adrenal body | See adrenal gland. (12 Dec 1998) |
| alveolar body | That portion of bone in either the maxilla or the mandible which surrounds and supports the teeth. (12 Dec 1998) |