| Jerne technique | A technique for measuring immunocompetence by quantitating the number of splenic antibody-forming cells found in a mouse that has been sensitised to sheep erythrocytes. The number of plaques formed correlates with the number of splenic antibody-forming cells. (05 Mar 2000) |
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| Judkins technique | A method of selective coronary artery catheterization utilizing the standard Seldinger technique through a percutaneous femoral artery puncture. (05 Mar 2000) |
| kleinschmidt monolayer technique | <technique> A method for preparing DNA for study under an electron microscope, the DNA molecules are spread as a thin, positively charged protein film onwater. The film is then transferred to a copper viewing grid andplaced under the microscope. (17 Dec 1997) |
| Ficoll-Hypaque technique | A density-gradient centrifugation technique for separating lymphocytes from other formed elements in the blood; the sample is layered onto a Ficoll-sodium metrizoate gradient of specific density; following centrifugation, lymphocytes are collected from the plasma-Ficoll interface. (05 Mar 2000) |
| flicker fusion frequency technique | A technique of perimetry using the criterion of critical fusion frequency. Synonym: flicker fusion frequency technique. (05 Mar 2000) |
| flush technique | <procedure> A technique for determining the systolic blood pressure in infants; the elevated limb is milked of blood from the hand or foot proximally; the blood pressure cuff is then inflated above the likely systolic pressure and the limb lowered; the cuff pressure is then gradually released until the blanched limb flushes. (05 Mar 2000) |
| long cone technique | The use of a cone distance of 14 inches or more in making oral roentgenographs. (05 Mar 2000) |
| affinity antibody | The measure of the interaction between molecules such as a receptor and its ligand. This interaction is reversible. (05 Mar 2000) |
| agglutinating antibody | 1. An antibody that causes clumping or agglutination of the bacteria or other cells which either stimulated the formation of the agglutinin, or contain immunologically similar, reactive antigen. Synonym: agglutinating antibody, immune agglutinin. 2. A substance, other than a specific agglutinating antibody, that causes organic particles to agglutinate, commonly qualified, e.g., plant agglutinin. (05 Mar 2000) |
| anaphylactic antibody | Antibody that has an affinity for certain kinds of cells, in addition to and unrelated to its specific affinity for the antigen that induced it, because of the properties of the Fc portion of the heavy chain. See: heterocytotropic antibody, homocytotropic antibody, cytotropic antibody test. Synonym: anaphylactic antibody, cytophilic antibody. (05 Mar 2000) |
| anti-basement membrane antibody | Autoantibodies to renal glomerular basement membrane antigens. (05 Mar 2000) |
| antibody | An immunoglobulin molecule that has a specific amino acid sequence by virtue of which it interacts only with the antigen that induced its synthesis in cells of the lymphoid series (especially plasma cells) or with antigen closely related to it. Antibodies are classified according to their ode of action as agglutinins, bacteriolysins, haemolysins, opsonins, precipitins, etc. (18 Nov 1997) |
| antibody affinity | A measure of the binding strength between antibody and a simple hapten or antigen determinant. It depends on the closeness of stereochemical fit between antibody combining sites and antigen determinants, on the size of the area of contact between them, and on the distribution of charged and hydrophobic groups. It includes the concept of "avidity," which refers to the strength of the antigen-antibody bond after formation of reversible complexes. (12 Dec 1998) |
| antibody aldolase | <enzyme> Prepared by reactive immuninization to catalyze a wide variety of aldol reactions and decarboxylations Registry number: EC 4.1.2.- Synonym: fab 33f12, aldolase catalytic antibody (26 Jun 1999) |
| antibody-coated bacteria test, urinary | Fluorescent antibody technique for visualizing antibody-bacteria complexes in urine. The presence or absence of antibody-coated bacteria in urine correlates with localization of urinary tract infection in the kidney or bladder, respectively. (12 Dec 1998) |