| malignant granuloma | Destruction of the nasal septum, hard palate, lateral nasal walls, paranasal sinuses, skin of the face, orbit and nasopharynx by an inflammatory infiltrate with atypical lymphocytic and histiocytic cells; presumably a form of lymphoma in most cases. An obsolete term for polymorphic reticulosis. Synonym: granuloma gangrenescens, malignant granuloma, midline malignant reticulosis granuloma. (05 Mar 2000) |
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| paracoccidioidal granuloma | A mycosis affecting the skin, mucous membranes, lymph nodes, and internal organs. It is caused by paracoccidioides brasiliensis. It is also called paracoccidioidal granuloma. (12 Dec 1998) |
| parasitic granuloma | Cutaneous leishmaniasis manifested as warty papules affecting primarily the lower limbs. (05 Mar 2000) |
| giant cell granuloma | <dermatology, oncology> A non-neoplastic lesion characterised by a proliferation of granulation tissue containing numerous multinucleated giant cells. It occurs on the gingiva and alveolar mucosa (occasionally on other soft tissues) where it presents as a soft red-blue haemorrhagic nodular swelling. It also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis), central refers to the jaw. Microscopically similar lesions occur in the tubular bones of the hands and feet, are considered neoplastic, and may have a malignant course. Identical bony lesions may be seen in hyperparathyroidism and cherubism. See: giant cell tumour of bone. Synonym: giant cell epulis. (05 Mar 2000) |
| reparative giant cell granuloma | <dermatology, oncology> A non-neoplastic lesion characterised by a proliferation of granulation tissue containing numerous multinucleated giant cells. It occurs on the gingiva and alveolar mucosa (occasionally on other soft tissues) where it presents as a soft red-blue haemorrhagic nodular swelling. It also occurs within the mandible or maxilla as a unilocular or multilocular radiolucency. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis), central refers to the jaw. Microscopically similar lesions occur in the tubular bones of the hands and feet, are considered neoplastic, and may have a malignant course. Identical bony lesions may be seen in hyperparathyroidism and cherubism. See: giant cell tumour of bone. Synonym: giant cell epulis. (05 Mar 2000) |
| reticulohistiocytic granuloma | <tumour> Obsolete term for reticulohistiocytoma. (05 Mar 2000) |
| periapical granuloma | Chronic nonsuppurative inflammation of periapical tissue resulting from irritation following pulp disease or endodontic treatment. (12 Dec 1998) |
| granuloma | <pathology> Chronic inflammatory lesion characterised by large numbers of cells of various types (macrophages, lymphocytes, fibroblasts, giant cells), some degrading and some repairing the tissues. (18 Nov 1997) |
| granuloma annulare | <dermatology> Benign granulomatous disease of unknown aetiology characterised by a ring of localised or disseminated papules or nodules on the skin and palisading histiocytes surrounding necrobiotic tissue resulting from altered collagen structures. (12 Dec 1998) |
| granuloma endemicum | <dermatology, infectious disease> The lesion occurring in cutaneous leishmaniasis. (05 Mar 2000) |
| granuloma faciale | <dermatology> Persistent well-demarcated nodules that usually appear on the face and consist of a dense dermal infiltrate of eosinophils and neutrophils, separated from the epidermis and hair follicles, with fibrinoid vasculitis. (05 Mar 2000) |
| granuloma, foreign-body | Histiocytic, inflammatory response to a foreign body. It consists of modified macrophages with multinucleated giant cells, in this case foreign-body giant cells (giant cells, foreign-b0dy), usually surrounded by lymphocytes. (12 Dec 1998) |
| granuloma gangrenescens | Destruction of the nasal septum, hard palate, lateral nasal walls, paranasal sinuses, skin of the face, orbit and nasopharynx by an inflammatory infiltrate with atypical lymphocytic and histiocytic cells; presumably a form of lymphoma in most cases. An obsolete term for polymorphic reticulosis. Synonym: granuloma gangrenescens, malignant granuloma, midline malignant reticulosis granuloma. (05 Mar 2000) |
| granuloma gravidarum | A pyogenic granuloma developing on the gingiva during pregnancy; thought to be related to hormonally altered response of the oral mucous membranes to local irritants such as bacterial plaque on adjacent teeth. Synonym: pregnancy tumour. (05 Mar 2000) |
| granuloma inguinale | <disease, microbiology> A rare sexually transmitted disease that is caused by Calymmatobacterium granulomatis. This infection is more common in the tropical and subtropical areas such as India, Guyana and new Guinea. There are approximately 100 cases reported annually in the United States. Men are affected more often than women. It is thought to be most commonly acquired through anal intercourse. Symptoms include a small red nodule on the genitalia that may form elevated masses of reddened tissue (granulation tissue). The lesions gradual spread and destroy genital tissue. Diagnosis is via tissue biopsy or culture. Treatment includes antibiotics. (27 Sep 1997) |