| fibrous skeleton of heart | A complex framework of dense collagen forming four fibrous rings (annuli fibrosi), which surround the ostia of the valves, a right and left fibrous trigone, formed by connecting the rings, and the membranous portions of the interatrial and interventricular septa; it is found in association with the base of the ventricles, i.e., at the level of the coronary sulcus; its functions include: 1) contributing reinforcement of the valvular ostia while providing attachment for the leaflets and cusps of the valves; 2) providing origin and insertion for the myocardium; and 3) serving as a sort of electrical "insulator," separating the electrically conducted impulses of the atria and ventricles and providing passage for the common atrioventricular bundle of conductive tissue through the right fibrous trigone and membranous interventricular septum. Synonym: cardiac fibrous skeleton, cardiac skeleton, skeleton of heart. (05 Mar 2000) |
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| fibrous tissue | Although most connective tissue has fibrillar elements, the term usually refers to tissue laid down at a wound site well vascularised at first (granulation tissue) but later avascular and dominated by collagen rich extracellular matrix, forming a scar. Excessive contraction and hyperplasia leads to formation of a keloid. (18 Nov 1997) |
| fibrous trigones of heart | See: right fibrous trigone, left fibrous trigone. (05 Mar 2000) |
| fibrous tubercle | A tubercle in which fibroblasts proliferate about the periphery (and into the cellular zones), eventually resulting in a rim or wall of cellular fibrous tissue or collagenous material around the tubercle. (05 Mar 2000) |
| fibrous tunic of corpus spongiosum | <anatomy> The thick layer of fibrous tissue surrounding the corpus spongiosum penis. It is thinner than the corresponding layer around each corpus cavernosum. Synonym: tunica albuginea corporis spongiosi, fibrous tunic of corpus spongiosum. (05 Mar 2000) |
| fibrous tunic of eye | The outer layer of the eyeball composed of the sclera and cornea. Synonym: tunica fibrosa bulbi, tunica externa oculi. (05 Mar 2000) |
| fibrous union | Union of fracture by fibrous tissue. See: nonunion. Synonym: faulty union. (05 Mar 2000) |
| fibrous xanthoma | <tumour> A fibrohistiocytic neoplasm. (05 Mar 2000) |
| left fibrous trigone | The part of the fibrous skeleton of the heart located in the interval between the left side of the left atrioventricular ring and the aortic ring. Synonym: trigonum fibrosum sinistrum. (05 Mar 2000) |