| SAR | scatter/air ratio; seasonal allergic rhinitis; sexual attitude reassessment; slowly adapting recepto... |
|---|---|
| SRS | schizophrenic residual state; sex reassignment surgery; Silver-Russell syndrome; simple repeat seque... |
| CER | capital expenditure review; ceramide; conditioned emotional response; control electrical rhythm; cor... |
| CR | calculation rate; calculus removed; calorie-restricted; cardiac rehabilitation; cardiac resuscitatio... |
| IR | drop of voltage across a resistor produced by a current; ileal resection; immune response; immunizat... |
| fractional dose | A definite fraction of a full dose; given repeatedly at short intervals so that the full dose is taken within a specified period, usually one day. Synonym: fractional dose. (05 Mar 2000) |
|---|---|
| L+ dose | The limes tod dose of diphtheria toxin, i.e., the smallest amount of toxin that, when mixed with one unit of antitoxin and injected subcutaneously into a 250-g guinea pig, results in death of the animal within 96 hours (based on the average in a series); on theoretical grounds, one might expect that the difference between the L+ and L0 dose's would be identical to 1 MLD, but this is not so in actual practice; with various toxic filtrates, the difference may range from several to more than 100 MLD's, indicating that the toxin-antitoxin combination is not a firm chemical union that occurs in constant proportions. (05 Mar 2000) |
| lethal dose | <pharmacology> The amount, or dosage, of a toxin necessary to cause death. (16 Mar 1998) |
| lethal dose 50 | <pharmacology> The amount, or dosage, of a toxin necessary to kill 50% of the experimental subjects. (16 Mar 1998) |
| Lf dose | The limes flocculation dose of diphtheria toxin, i.e., the smallest amount of toxin that, when mixed with one unit of antitoxin, yields the most rapid flocculation in the Ramon test (in vitro); in general, the Lf dose is slightly less than the Lr dose. (05 Mar 2000) |
| loading dose | <pharmacology> A quantity higher than the average or maintenance dose, used at the initiation of therapy to rapidly establish a desired level of the drug (18 Nov 1997) |
| Lo dose | <pharmacology> The limes nul dose of diphtheria toxin, i.e., the largest amount of toxin that, when mixed with one unit of antitoxin and injected subcutaneously into a 250-g guinea pig, yields no recognizable reaction in the average of a series; actually, the Lod. Is usually recorded as the one that causes a barely perceptible local oedema at the site of inoculation. (05 Mar 2000) |
| Lr dose | The limes reacting dose of diphtheria toxin, i.e., the smallest amount of toxin that, when mixed with one unit of antitoxin and injected intracutaneously in the shaved skin of a susceptible guinea pig, yields a minimal, positive reaction and inflammation localised to the region of the injection; the Lrd. Closely approximates the Lod., as would be expected, inasmuch as a slight excess of unneutralised toxin results in a reaction. (05 Mar 2000) |
| anamnestic response | <immunology> Archaic term now replaced by such terms as secondary immune response, immune memory. (18 Nov 1997) |
| audiometry, evoked response | A form of electrophysiologic audiometry in which an analog computer is included in the circuit to average out ongoing or spontaneous brain wave activity. A characteristic pattern of response to a sound stimulus may then become evident. Evoked response audiometry is known also as electric response audiometry. (12 Dec 1998) |
| auditory brainstem response audiometry | An electrophysiologic measure of auditory function utilizing responses produced by the auditory nerve and the brainstem to repetitive acoustic stimuli. (05 Mar 2000) |
| biological response modifier | <pharmacology, oncology> A substance used in adjuvant therapy that takes advantage of the bodys own natural defense mechanisms to inhibit the growth of a tumour. (16 Dec 1997) |
| biological response modifiers | Substances that stimulate the body's response to infection and disease. The body naturally produces small amounts of these substances. Scientists can produce some of them in the laboratory in large amounts and use them in cancer treatment. Also called BRMs. (12 Dec 1998) |
| biphasic response | Two separate and distinct responses that are separated in time, immediate reaction to an antigenic challenge followed by a recurrence of symptoms after an interval of quiescence. (05 Mar 2000) |
| booster response | The response of the immune system to the second or subsequent occasion on which it encounters a specific antigen. (18 Nov 1997) |