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equilibrium constant <chemistry> The ratio of the reverse and forward rate constants for a reaction of the type:
A + B = AB
at equilibrium the equilibrium constant (K) equals the product of the concentrations of reactants divided by the concentration of product and has dimensions of concentration.
Kd = (concentration A.concentration B) / (concentration AB).
The affinity constant (Ka) is the reciprocal of the equilibrium constant.
Dimension: moles per litre. In general the concept of Kd is more readily understood than that of Ka, for example: in considering the conversion of A to AB by the binding of ligand B, the Kd = B when A = AB. Thus Kd is equal to the ligand concentration which produces half maximal conversion (response).
(10 Jan 1998)
universal gas constant <radiobiology> R = 8.314 x 10^7 ergs per degree C per mole.
(09 Oct 1997)
flotation constant Characteristic sedimentation behaviour of a lipoprotein fraction of plasma in a centrifugal field in a medium of appropriate density, achieved by adding a salt or D2O to the plasma.
Synonym: negative S, Svedberg of flotation.
(05 Mar 2000)
law of constant numbers in ovulation The number of ova discharged at each ovulation is nearly constant for any given species.
(05 Mar 2000)
auditory field The space included within the limits of hearing of a definite sound, as of a tuning fork.
(05 Mar 2000)
bright field illumination <microscopy> The method of lighting the specimen with a solid cone of rays. Transmitted bright field illumination is performed by a substage condenser. Reflected bright field illumination is performed by a vertical illuminator.
Compare: dark field illumination
(05 Aug 1998)
bright field imaging <microscopy> An imaging mode in a transmission electron microscopy that uses only unscattered Electrons to form the image. Contrast in such an image is due entirely to mass-thickness variations in amorphous samples, and may include diffraction contrast in crystalline samples.
(05 Aug 1998)
bright field microscopy <technique> Optical microscopy, in which absorption to a great extent and diffraction to a minor extent give rise to the image, as opposed to phase contrast or interference methods of microscopy.
(18 Nov 1997)
Broca's field The posterior part of the inferior frontal gyrus of the left or dominant hemisphere, corresponding approximately to Brodmann's area 44; Broca identified this region as an essential component of the motor mechanisms governing articulated speech.
Synonym: Broca's area, Broca's field, motor speech centre.
(05 Mar 2000)
cardioid dark field condenser <microscopy> A condenser designed with two reflecting surfaces, the first, a spherical surface which reflects the rays to a second, cardioid (heart-shaped) surface. The virtue in such an arrangement is that, if the cardioid surface is of true figure, the lens is both achromatic and aplanatic. It has a limiting numerical aperture of about 1.0. Thus objectives of a greater numerical aperture cannot be used successfully with it. A true cardioid figure is the trace of a point on the circumference of a circle rolling around an equal, fixed circle.
(05 Aug 1998)
magnetic field The sphere of influence of a magnet.
(05 Mar 2000)
magnetic field gradient In magnetic resonance imaging, a magnetic field that varies with location, superimposed on the uniform field of the magnet, to alter the resonant frequency of nuclei and allow recovery of their spatial position.
Synonym: field gradient.
(05 Mar 2000)
paraboloid dark field condenser <microscopy> A lens of parabolic shape. The vertex end is ground back so that its focus can be brought into coincidence with the specimen on the slide. A central stop is provided to block the central rays. It is used chiefly for medium- power work.
(05 Aug 1998)
receptive field That part of the retina whose photoreceptors (rods and cones) pertain to a single optic nerve fibre. The response of a neuron to stimulation of its receptive field depends on the type of neuron and the part of the field that is illuminated; an "on-centre" neuron is stimulated by light falling at the centre of its receptive field and inhibited by light falling at the periphery; an "off-centre" neuron reacts in exactly the opposite fashion; that is, it is inhibited by light falling at the centre of its receptive field. In either case, the net response depends on a complex switching action in the retina. When an entire receptive field is equally illuminated, the response of receptors at the centre of the field predominates.
(05 Mar 2000)
visual field The area simultaneously visible to one eye without movement; often measured by means of a bowl perimeter located 330 mm from the eye.
(05 Mar 2000)
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