caffeic acid
| replacement vector | A cloning vector, such as a bacteriophage, in which some of the DNA of the vector can be replaced with foreign DNA. (09 Oct 1997) |
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| hip replacement | Surgery to replace all or part of the hip joint with an artificial device that re-establishes normal hip joint motion. Indicated in cases of severe intractable degenerative arthritis (DJD). (27 Sep 1997) |
| hormone replacement therapy | In females, treatment with sex hormones for a number for reasons, including menopause, partial or full hysterectomy, or amenorrhoea.In women, treatment with sex hormones is indicated for a number of reasons, including menopause, partial or full hysterectomy, or amenorrhoea. After menopause, conjugated oestrogens, estradiol, or estrone sulfate are given to reduce pain during intercourse, limit blood vessel effects, and prevent loss of bone mass. After radical hysterectomy, conjugated oestrogens are given for similar reasons. After menopause or partial hysterectomy, progestin is administered at the same time to offset an increased risk of endometrial cancer. In some amenorrhoeas, oestrogen is given to restore menses; if the therapy is unsuccessful, this may indicate the presence of pathology, for instance, pituitary tumour. Benefits for postmenopausal women include a lowered risk of heart attack (oestrogen lowers LDL and raises HDL levels), and prevention of osteoporosis, since the rate of bone loss is directly linked to a drop in oestrogen levels (see perimenopause). Medical opinion about the hazard posed by such therapy remains divided. Some studies have indicated increased incidence of breast cancer; however, a comprehensive 1992 review of the literature contradicted this finding. (05 Mar 2000) |
| oestrogen replacement therapy | <endocrinology, gynaecology> The use of oestrogenic substances in postmenopausal or other oestrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, dyspareunia, and progressive development of osteoporosis. (12 Dec 1998) |
| ossicular replacement | Surgical insertion of an implant to replace one or more of the ear ossicles. (12 Dec 1998) |
| total knee joint replacement | Surgery involving the replacement of the knee joint with artificial components which reestablishes normal joint function. Indicated in cases of severe knee fracture or degenerative arthritis (DJD) unresponsive to medical therapy. (27 Sep 1997) |
| energy replacement time | <radiobiology> Time required for a plasma to lose (via radiation or other loss mechanisms) an amount of energy equal to its average kinetic energy. (09 Oct 1997) |
| enzyme replacement therapy | A type of medical treatment for patients who lack an important enzyme, the missing enzyme is injected into the patient. (09 Oct 1997) |
| amino- | <prefix> Prefix denoting a compound containing the radical, -NH2. Origin: an(monia) + in(e) + -o- (05 Mar 2000) |
| amino acids | Organic compounds that generally contain an amino (-nh2) and a carboxyl (-cooh) group. Twenty alpha-amino acids are the subunits which are polymerised to form proteins. (12 Dec 1998) |
| amino acids, branched-chain | Amino acids which have a branched carbon chain. (12 Dec 1998) |
| amino acids, cyclic | A class of amino acids characterised by a closed ring structure. (12 Dec 1998) |
| amino acids, peptides, and proteins | Amino acids and chains of amino acids connected by peptide linkages. (12 Dec 1998) |
| amino acyl-tRNA ligases | <enzyme> Any of the group of ligases that catalyses the ATP-driven formation of a bond between an amino acid and a trna, activating the amino acids as a step in protein synthesis. Individual enzymes are highly specific for one amino acid and for any trna corresponding to that amino acid. Registry number: EC 6.1.1. (12 Dec 1998) |
| amino alcohols | Compounds possessing both a hydroxyl (-oh) and an amino group (-nh2). (12 Dec 1998) |