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colloid adenoma <tumour> A follicular adenoma of the thyroid, composed of large follicles containing colloid.
Synonym: macrofollicular adenoma.
(05 Mar 2000)
pituitary adenoma <radiology> Benign, slow-growing, arises from adenohypophysis (anterior lobe), 5-18% of all intracranial neoplasms plain film (unreliable): enlargement of sella and sloping of the sella floor, erosion of the anterior and posterior clinoid, erosion of the dorsum sellae, calcified in less than10%, may present as a mass in the nasopharynx functioning microadenoma, less than10 mm, 20-30% of pituitary adenomas, types: prolactinoma, corticotrophic adenoma, somatotrophic adenoma, nonfunctioning macroadenoma, more than 10 mm, 70-80% of pituitary adenomas
(12 Dec 1998)
pleomorphic adenoma A tumour composed of salivary gland epithelium and fibrous tissue with mucoid or cartilaginous areas.
Synonym: pleomorphic adenoma.
(05 Mar 2000)
corticotrophic adenoma <oncology, tumour> ACTH-secreting tumour, posterior lobe of the pituitary (central location), usually less than 5mm.
See: Cushing disease, pituitary adenoma.
(12 Dec 1998)
polypoid adenoma A polyp that consists of benign neoplastic tissue derived from glandular epithelium.
Synonym: cellular polyp, polypoid adenoma.
(05 Mar 2000)
prolactin-producing adenoma <tumour> A pituitary adenoma composed of prolactin-producing cells; it gives rise to symptoms of nonpuerperal amenorrhoea and galactorrhoea (Forbes-Albright syndrome) in women and to impotence in men.
Synonym: prolactinoma.
(05 Mar 2000)
hepatic adenoma <radiology> Liver cell adenoma (LCA), rare, benign, F more than M, atypical hepatocytes, no bile ducts or Kuppfer cells (unlike FNH), haemorrhage common, NM: cold nodule associated with: oral contraceptives, type 1 glycogen storage disease (von Gierke)
(12 Dec 1998)
hepatocellular adenoma <radiology> Liver cell adenoma (LCA), rare, benign, F more than M, atypical hepatocytes, no bile ducts or Kuppfer cells (unlike FNH), haemorrhage common, NM: cold nodule associated with: oral contraceptives, type 1 glycogen storage disease (von Gierke)
(12 Dec 1998)
prostatic adenoma <tumour> A term used for the growth in benign prostatic hyperplasia.
(05 Mar 2000)
sebaceous adenoma <tumour> A benign neoplasm of sebaceous tissue, with a predominance of mature secretory sebaceous cells.
Compare: adenoma sebaceum.
(05 Mar 2000)
Hurthle cell adenoma <tumour> An uncommon type of thyroid tumour characterised by abundant eosinophilic cytoplasm containing numerous mitochondria. Often malignant with widespread metastases; rarely takes up radioiodine.
See: Hurthle cell tumour.
(05 Mar 2000)
somatotrophic adenoma <radiology> Elevated growth hormone (greater than10 ng/ml), gigantism, acromegaly see: pituitary adenoma
(12 Dec 1998)
nephrogenic adenoma <tumour> A benign tumour of the urinary bladder mucosa, composed of glandular structures resembling renal tubules.
(05 Mar 2000)
null-cell adenoma <tumour> An adenoma of the hypophysis composed of cells for which there is no overt evidence or hormone production, but which usually produces hypopituitarism and visual disturbances by compression of adjacent structures; approximately one third of these tumours have cells with abundant mitochondria (oncocytes) that are somewhat larger than the monocytic null cells.
Synonym: undifferentiated cell adenoma.
(05 Mar 2000)
islet cell adenoma <tumour> A benign neoplasm of the pancreas composed of tissue similar in structure to that of the islets of Langerhans; it may contain functioning beta cells, and may cause hypoglycaemia.
See: insulinoma.
Synonym: nesidioblastoma.
(05 Mar 2000)
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