| lymphocyte function-associated antigen-1 | A heterodimer molecule widely expressed on cells of haematopoietic origin. Cd11a antigen comprises the alpha chain and the CD18 antigen (antigens, CD18) the beta chain. Lfa-1 is a major receptor of T-cells, B-cells, and granulocytes. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by natural killer cells and granulocytes. Intracellular adhesion molecule-1 (icam-1) has been defined as a ligand for lfa-1. (12 Dec 1998) |
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| lymphoma, mucosa-associated lymphoid tissue | Extranodal lymphoma of lymphoid tissue associated with mucosa that is in contact with exogenous antigens. Many of the sites of these lymphomas, such as the stomach, salivary gland, and thyroid, are normally devoid of lymphoid tissue. They acquire malt tissue as a result of an immunologically mediated disorder. (12 Dec 1998) |
| lysosome associated membrane glycoprotein | <protein> Lysosome specific integral membrane glycoproteins. Long luminal domain, short transmembrane domain, very short cytoplasmic tail. Function not yet clear. (18 Nov 1997) |