| KE | Kendall compound E; kinetic energy |
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| LOC | laxative of choice; level of consciousness; liquid organic compound; locus of control; loss of consc... |
| M+Am | compound myopic astigmatism |
| MLC | minimum lethal concentration; mixed leukocyte culture; mixed ligand chelate; mixed lymphocyte concen... |
| NOSAC | nonsteroidal anti-inflammatory compound |
| inorganic compound | A compound in which the atoms or radicals consist of elements other than carbon and are typically held together by electrostatic forces rather than by covalent bonds; often are capable of dissociation into ions in polar solvents (e.g., H2O). Compare: organic compound. (05 Mar 2000) |
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| isocyclic compound | Any compound in which the constituent atoms, or any part of them, form a ring. Used mainly in organic chemistry where: 1) numerous compound's contain rings of carbon atoms (carbocyclic compound's) or carbon atoms plus one or more atoms of other types (heterocyclic compound's), usually nitrogen, oxygen, or sulfur; 2) where the atoms in the ring are all of the same element (homocyclic or isocyclic compound); 3) where the ring is saturated or contains nonconjugated double bonds (alicyclic compound), the compound is similar in properties to the corresponding acyclic compound (e.g., cyclohexane resembles hexane); 4) where the ring contains conjugated double bonds in a closed loop in which there are 4n + 2 (where n is an integer) delocalised π electrons (Huckel's rule) (aromatic compound; e.g., benzene, pyridine), it is more stable than the corresponding saturated ring and exhibits unusual chemical properties characteristic of itself and not of other types of rings or of acyclic compound's. These aromatic compounds have the ability to sustain an induced ring current. Synonym: closed chain compound, ring compound. (05 Mar 2000) |
| open chain compound | An organic compound in which the chain does not form a ring. Synonym: aliphatic compound, open chain compound. (05 Mar 2000) |
| organic compound | <chemistry> A compound containing carbon. (11 Jan 1998) |
| lens, compound | <microscopy> A lens composed of two or more separate pieces of glass or other optical maternal. These component pieces or elements may or may not be cemented together. A common form of compound lens is a two-element objective, one element being a converging lens of crown glass and the other a diverging lens of flint glass. The combination of suitable glasses or other optical materials (plastics, minerals) properly ground and polished reduces aberrations normally present in a single lens. (05 Aug 1998) |
| acidic amino acid | An Amino acid with a second acid moiety, e.g., glutamic acid, aspartic acid, cysteic acid. (05 Mar 2000) |
| activated amino acid | The product formed by the condensation of the acyl radical of an amino acid and adenosine 5'-monophosphate (originally in the form of adenosine 5'-triphosphate, with elimination of a pyrophosphoric group). Formed in the first step of protein biosynthesis. Synonym: activated amino acid. (05 Mar 2000) |
| alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid | <chemical> Alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid. An ibotenic acid homolog and glutamate agonist. The compound is the defining agonist for the ampa subtype of glutamate receptors (receptors, ampa). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies. Pharmacological action: excitatory amino acid agonists. Chemical name: 4-Isoxazolepropanoic acid, alpha-amino-2,3-dihydro-5-methyl-3-oxo- (12 Dec 1998) |
| alpha-amino acid | Typically, an amino acid of the general formula R-CHNH2-COOH (i.e., the NH2 in the a position); the l forms of these are the hydrolysis products of proteins. In rarer usages, this class of molecules also includes alpha-amino phosphoric acids and alpha-aminosulfonic acids. (05 Mar 2000) |
| alpha-amino acid esterase | <enzyme> Converts alpha-amino acid esters and water to alpha-amino acids and alcohol Registry number: EC 3.1.1.43 Synonym: alpha-amino acid ester hydrolase (26 Jun 1999) |
| alpha-amino-beta-ketoadipic acid | 2-Amino-3-oxo-1,6-hexanedioic acid;an intermediate of porphobilinogen synthesis formed by d-aminolevulinic acid synthase from succinyl-CoA and glycine; it rapidly decarboxylates to d-aminolevulinic acid. (05 Mar 2000) |
| amino- | <prefix> Prefix denoting a compound containing the radical, -NH2. Origin: an(monia) + in(e) + -o- (05 Mar 2000) |
| amino acid | <biochemistry> A class of organic molecules that containing an amino group and can combine in linear arrays to form proteins in living organisms. There are twenty common amino acids: alanine, arginine, aspargine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, and valine. They are key components in all living things from which proteins are synthesised by formation of peptide bonds during ribosomal translation of messenger RNA. All the amino acids have the L configuration, except glycine which is not optically active. Other amino acids occurring in proteins, such as hydroxyproline in collagen, are formed by post translational enzymatic modification of amino acid residues in polypeptide chains. There are also several important amino acids, such as the neurotransmitter y aminobutyric acid, that have no relation to proteins. Amino acids can now be produced by biotechnology in bulk using fermentation and biotransformation. Acronym: AA (13 Nov 1997) |
| amino acid activating enzyme | <enzyme> Enzymes catalyzing the formation of a specific aminoacyl-tRNA from an amino acid and adenosine 5'-triphosphate with the concomitant formation of adenosine 5'-monophosphate and pyrophosphate. Synonym: amino acid activating enzyme, aminoacyl-tRNA ligases. (05 Mar 2000) |
| amino acid activation | The first step of protein synthesis, whereby an amino acid reacts with adenosine triphosphate in the presence of aminoacyl RNA synthetase to produce an amino acid adenylate, which provides the energy necessary for the attachment of the amino acid to a specific transfer RNA molecule. (12 Dec 1998) |
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