aminoglycoside N(3')-acetyltransferase | <enzyme> Catalyses the reaction of CoA and acetyl-2-deoxystreptamine antibiotic to yield acetyl-CoA and a 2-deoxystreptamine antibiotic; has broad specificity; acts on gentamicin, tobramycin, sisomicin, netilmicin, kanamycin, neomycin and apramycin Registry number: EC 2.3.1.81 Synonym: aac(3)-iv, aminoglycoside-(3)-n-acetyltransferase iv (26 Jun 1999) |
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aminoglycoside N(6')-acetyltransferase | <enzyme> The antibiotic kanamycin, gentamicin, tobramycin, and neomycin can act as an acceptor; has to be 6'-acetyltransferase Registry number: EC 2.3.1.82 Synonym: amikacin acetyltransferase, aminoglycoside-6'-n-acetyltransferase, gentamicin 6'-acetyltransferase, 6' gat gene product, aac(6') (26 Jun 1999) |
aminoglycoside N1-acetyltransferase | <enzyme> Monoacetylates apramycin, butirosin, lividomycin and paromomycin at the c1 amino group and diacetylates ribostamycin and neomycin, at the c1 amino and possibly at the 6' amino group Registry number: EC 2.3.1.- Synonym: acc1 enzyme, paromomycin acetyltransferase (26 Jun 1999) |
aminoglycoside phosphoribosyltransferase | <enzyme> Coded by neo-gene; involved in kanamycin resistance; no other information given on reaction 8/93 Registry number: EC 2.4.2.- Synonym: aminoglycosidephosphoribosyltransferase (26 Jun 1999) |
aminohippuric acids | A group of glycine amides of aminobenzoic acids. (12 Dec 1998) |
aminohydrolases | <enzyme> Registry number: EC 3.5.4. (12 Dec 1998) |
aminoimidazole carboxamide | <chemical> 5-amino-1h-imidazole-4-carboxamide. An imidazole derivative which is a metabolite of the antineoplastic agent bic and dic. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases. Chemical name: 1H-Imidazole-4-carboxamide, 5-amino- (12 Dec 1998) |
aminoisobutyric acids | A group of compounds that are derivatives of the amino acid 2-amino-2-methylpropanoic acid. (12 Dec 1998) |
aminolevulinic acid | <chemical> Chemical name: Pentanoic acid, 5-amino-4-oxo- (12 Dec 1998) |
aminolysis | Replacement of a halogen in an alkyl or aryl molecule by an amine radical, with elimination of hydrogen halide. (05 Mar 2000) |
aminomethyltransferase | <enzyme> T-protein component of glycine cleavage system which oxidatively decarboxylates glycine Registry number: EC 2.1.2.10 Synonym: glycine synthase system, t-protein, glycine cleavage system, glycine synthase, gcvt gene product (26 Jun 1999) |
aminometradine | 1-allyl-6-amino-3-ethyluracil;synthetic uracil derivative; an orally effective diuretic that is believed to act by inhibiting the reabsorption of sodium by the renal tubules; used in the treatment of oedema due to congestive heart failure, liver disease, pregnancy, and certain drugs. Synonym: aminometradine. (05 Mar 2000) |
aminometramide | 1-allyl-6-amino-3-ethyluracil;synthetic uracil derivative; an orally effective diuretic that is believed to act by inhibiting the reabsorption of sodium by the renal tubules; used in the treatment of oedema due to congestive heart failure, liver disease, pregnancy, and certain drugs. Synonym: aminometradine. (05 Mar 2000) |
aminooligopeptidase | <enzyme> Human, intestinal brush-border enzyme; acts on oligopeptides with bulky side-chains removing n-terminal amino acids until dipeptide remains Registry number: EC 3.4.11.- Synonym: amino-oligopeptidase (26 Jun 1999) |
aminooxyacetic acid | <chemical> (aminooxy)acetic acid. A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues. Pharmacological action: enzyme inhibitors, gaba agents. Chemical name: Acetic acid, (aminooxy)- (12 Dec 1998) |