| tryptamine-strophanthidin | A semisynthetic cardiac glycoside that is a condensation product of strophanthidin and tryptamine; given orally, it has a rapid onset and short duration of cardiac action. (05 Mar 2000) |
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| tryptase | <enzyme> Isolated from mouse; prior to 1993 tryptase was indexed as tosylarginine methyl ester hydrolase Pharmacological action: inflammation mediators, mitogens Registry number: EC 3.4.21.59 Synonym: mast cell tryptase 2, mmcp-7, human mast cell tryptase, mast cell protease 7, mast cell tryptase, granzyme k (26 Jun 1999) |
| tryptic | <physiology> Relating to trypsin or to its action; produced by trypsin; as, trypsin digestion. Source: Websters Dictionary (01 Mar 1998) |
| tryptonaemia | The presence of tryptone in the circulating blood. (05 Mar 2000) |
| tryptone | <physiology> The peptone formed by pancreatic digestion; so called because it is formed through the agency of the ferment trypsin. Source: Websters Dictionary (01 Mar 1998) |
| tryptophan | <amino acid> One of the 20 amino acids found in proteins. Essential dietary component in humans. Precursor of nicotinamide. (18 Nov 1997) |
| tryptophan 2,3-dioxygenase | An oxidoreductase catalyzing the reaction of l-tryptophan and O2 to produce l-N-formylkynurenine; an adaptive enzyme, the level (in the liver) being controlled by adrenal hormones; a step in tryptophan catabolism; also, a step in the synthesis of NAD+ from tryptophan. Synonym: pyrrolase, tryptophan oxygenase, tryptophan pyrrolase, tryptophanase. (05 Mar 2000) |
| tryptophan 2-methyltransferase | <enzyme> From streptomyces laurentii; catalyses the transfer of a methyl group from s-adenosylmethionine to the c-2 carbon of tryptophan resulting in alpha-methyltryptophan; involved in the biosynthesis of thiostrepton Registry number: EC 2.1.1.- Synonym: s-adenosylmethionine-tryptophan 2-methyltransferase (26 Jun 1999) |
| tryptophan 2-monooxygenase | <enzyme> Forms indole-3-acetamide Registry number: EC 1.13.12.3 (26 Jun 1999) |
| tryptophan C-methyltransferase | <enzyme> Catalyses transfer of methyl group from s-adenosylmethionine to c-3 of tryptophan resulting in beta-methyltryptophan; involved in streptonigrin biosynthesis Registry number: EC 2.1.1.- (26 Jun 1999) |
| tryptophan decarboxylase | <enzyme> An enzyme that catalyses the decarboxylation of l-dopa to dopamine, of l-tryptophan to tryptamine, and of l-hydroxytryptophan to serotonin; important in the biosynthetic pathway of catecholamines and melanin. Synonym: dopa decarboxylase, hydroxytryptophan decarboxylase, tryptophan decarboxylase. (05 Mar 2000) |
| tryptophan desmolase | <enzyme> An enzyme that catalyses the conversion of l-serine and 1-(indol-3-yl)glycerol 3-phosphate to l-tryptophan and glyceraldehyde 3-phosphate. It is a pyridoxal phosphate protein that also catalyses the conversion of serine and indole into tryptophan and water and of indoleglycerol phosphate into indole and glyceraldehyde phosphate. Chemical name: L-Serine hydro-lyase (adding indoleglycerol-phosphate) Registry number: EC 4.2.1.20 (12 Dec 1998) |
| tryptophan hydroxylase | <enzyme> An enzyme that catalyses the hydroxylation of tryptophan to 5-hydroxytryptophan in the presence of NADPH and molecular oxygen. It is important in the biosynthesis of serotonin. Chemical name: L-tryptophan,tetrahydropteridine:oxygen oxidoreductase (5-hydroxylating) Registry number: EC 1.14.16.4 (12 Dec 1998) |
| tryptophan oxygenase | <enzyme> A protohemoprotein. Forms formylkynurenine from l-tryptophan and molecular oxygen. Chemical name: L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing) Registry number: EC 1.13.11.11 (12 Dec 1998) |
| tryptophan pyrrolase | An oxidoreductase catalyzing the reaction of l-tryptophan and O2 to produce l-N-formylkynurenine; an adaptive enzyme, the level (in the liver) being controlled by adrenal hormones; a step in tryptophan catabolism; also, a step in the synthesis of NAD+ from tryptophan. Synonym: pyrrolase, tryptophan oxygenase, tryptophan pyrrolase, tryptophanase. (05 Mar 2000) |