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thymokinetic Activating the thymus gland.
Origin: thymus + G. Kinesis, movement
(05 Mar 2000)
thymol <chemistry> A phenol derivative of cymene, C10H13.OH, isomeric with carvacrol, found in oil of thyme, and extracted as a white crystalline substance of a pleasant aromatic odour and strong antiseptic properties.
Synonym: hydroxy cymene.
Origin: Thyme + -ol.
Source: Websters Dictionary
(01 Mar 1998)
thymol blue A dye used as an acid-base indicator, with a pK value at 1.7 and another at 8.9; red at pH values below 1.2, yellow between 2.8 and 8.0, and blue above 9.6.
(05 Mar 2000)
thymol iodide C20H24I2O2;has been used as a substitute for iodoform in skin diseases, wounds, ulcers, purulent rhinitis, otitis, etc.
(05 Mar 2000)
thymol turbidity test Precipitation of abnormal proportions of albumin and globulin from the serum of patients with liver disease by addition of thymol. Although popular in the past it has been superseded by quantitative determination of specific proteins and direct measurement of liver enzymes.
Synonym: Maclagan's test, Maclagan's thymol turbidity test.
(05 Mar 2000)
thymolphthalein <chemical> 5',5''-diisopropyl-2',2''-dimethylphenolphthalein. Used as a pH indicator and as a reagent for blood after decolorizing the alkaline solution by boiling with zinc dust.
Pharmacological action: indicators and reagents, phthalein dyes.
Chemical name: 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxy-2-methyl-5-(1-methylethyl)phenyl)-
(12 Dec 1998)
thymoma <oncology, tumour> A tumour of thymic origin.
(18 Nov 1997)
thymonuclease <enzyme> An enzyme capable of hydrolyzing highly polymerised DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyses endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA.
Registry number: EC 3.1.21.1
(12 Dec 1998)
thymopentin <chemical> N-(n-(n-(n2-l-arginyl-l-lysyl)-l-alpha-aspartyl)-l-valyl)-l-tyrosine. Synthetic pentapeptide corresponding to the amino acids 32-36 of thymopoietin and exhibiting the full biological activity of the natural hormone. It is an immunomodulator which has been studied for possible use in the treatment of rheumatoid arthritis, aids, and other primary immunodeficiencies.
Pharmacological action: adjuvants, immunologic.
Chemical name: L-Tyrosine, N-(N-(N-(N2-L-arginyl-L-lysyl)-L-alpha-aspartyl)-L-valyl)-
(12 Dec 1998)
thymopoietin Formerly called thymin; a polypeptide hormone that induces differentiation of lymphocytes to thymocytes.
See: thymic lymphopoietic factor.
(05 Mar 2000)
thymopoietins Two closely related polypeptides (molecular weight 7,000) isolated from the thymus gland. These hormones induce the differentiation of prothymocytes to thymocytes within the thymus. They also cause a delayed impairment of neuromuscular transmission in vivo and are therefore believed to be the agent responsible for myasthenia gravis.
(12 Dec 1998)
thymoprival Thymoprivicthymoprivous
Relating to or marked by premature atrophy or removal of the thymus.
Origin: thymus + L. Privus, deprived of
(05 Mar 2000)
thymosin <biochemistry> Peptide (28 amino acids) that restores aspects of immune function in vivo and in vitro. Possibly a thymic hormone.
(18 Nov 1997)
thymosin _ 4 Small protein (5 kD: 43 residues) found in large amounts in many vertebrate cells (approximately 0.2 mM in neutrophils) and that binds G actin thereby inhibiting polymerisation.
(18 Nov 1997)
thymoxamine <chemical> (2-(4-acetoxy-2-isopropyl-5-methylphenoxy)ethyl)dimethylamine. An alpha-adrenergic blocking agent that is used in raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents.
Pharmacological action: adrenergic alpha-antagonists, miotics, sympatholytics, vasodilator agents.
Chemical name: Phenol, 4-(2-(dimethylamino)ethoxy)-2-methyl-5-(1-methylethyl)-, acetate (ester)
(12 Dec 1998)
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