| ribonucleoproteins, small, u4-u6 | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the u4-u6 snrnp along with the u5 snrnp preassemble into a single 25s particle that binds to the u1 and u2 snrnps and the substrate to form mature spliceosomes. There is also evidence for the existence of individual u4 or u6 snrnps in addition to their organization as a u4-u6 snrnp. (12 Dec 1998) |
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| ribonucleoproteins, small, u5 | A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the u5 snrnp along with u4-u6 snrnp preassemble into a single 25s particle that binds to the u1 and u2 snrnps and the substrate to form mature spliceosomes. (12 Dec 1998) |
| RNA, small nuclear | Short chains of RNA found in the nucleus. Their function is to remove the introns (nontranslated intervening sequences) from mRNA precursors, thereby bringing the two exons (coding segments) together into correct juxtaposition for enzymatic splicing at the correct point. The resulting mRNA is now ready to leave the nucleus. (12 Dec 1998) |
| sarcoma, small cell | A sarcoma characterised by the presence of small cells, cells measuring 9-14 micrometers with a faint or indistinct rim of cytoplasm and an oval-to-elongated nucleus with relatively dense chromatin. (12 Dec 1998) |
| proximal small bowel disease | <radiology> Giardia, eosinophilic gastroenteritis, Zollinger-Ellison (12 Dec 1998) |
| small | 1. Having little size, compared with other things of the same kind; little in quantity or degree; diminutive; not large or extended in dimension; not great; not much; inconsiderable; as, a small man; a small river. "To compare Great things with small." (Milton) 2. Being of slight consequence; feeble in influence or importance; unimportant; trivial; insignificant; as, a small fault; a small business. 3. Envincing little worth or ability; not large-minded; sometimes, in reproach, paltry; mean. "A true delineation of the smallest man is capable of interesting the reatest man." (Carlyle) 4. Not prolonged in duration; not extended in time; short; as, after a small space. 5. Weak; slender; fine; gentle; soft; not loud. "A still, small voice." Great and small,of all ranks or degrees; used especially of persons. "His quests, great and small." . Small arms, muskets, rifles, pistols, etc, in distinction from cannon. Small beer. See Beer. Small coal. Little coals of wood formerly used to light fires. Coal about the size of a hazelnut, separated from the coarser parts by screening. Small craft, various small textile articles, as tapes, braid, tringe, and the like. Origin: OE. Small, AS. Sm$l; akin to D. Smal narrow, OS. & OHG. Smal small, G. Schmal narrow, Dan. & Sw. Smal, Goth. Smals small, Icel. Smali smal cattle, sheep, or goats; cf. Gr. A sheep or goat. Source: Websters Dictionary (01 Mar 1998) |
| small-area analysis | A method of analyzing the variation in utilization of health care in small geographic or demographic areas. It often studies, for example, the usage rates for a given service or procedure in several small areas, documenting the variation among the areas. By comparing high- and low-use areas, the analysis attempts to determine whether there is a pattern to such use and to identify variables that are associated with and contribute to the variation. (12 Dec 1998) |
| small arteries | Unnamed muscular artery's, usually with fewer than six or seven layers of muscle. (05 Mar 2000) |
| small bowel dilatation | <radiology> Mnemonic: SOS, sprue, obstruction / ileus, scleroderma (collagen-vascular disease) normal width: less than 3 cm (12 Dec 1998) |
| small bowel disease | <radiology> Main feature, nodules, dilatation, thick folds distribution, localised, generalised, includes stomach, proximal, terminal ileum (TI), mesentery (12 Dec 1998) |
| small bowel disease involving mesentery | <radiology> Lymphoma, metastasis, retractile mesenteritis (12 Dec 1998) |
| small bowel disease involving stomach | <radiology> Lymphoma, eosinophilic gastroenteritis, Zollinger-Ellison syndrome (12 Dec 1998) |
| small bowel disease involving terminal ileum | <radiology> Crohn's, TB, Yersinia (12 Dec 1998) |
| small bowel enema | Radiographic examination of the small intestine, by retrograde filling from the contrast-filled large bowel. (05 Mar 2000) |
| small bowel infiltration | <radiology> Whipple disease (proximal small bowel), small bowel lymphoma, amyloidosis, Waldenstrom macrogloblinaemia, sprue, eosinophilic gastroenteritis, abetalipoproteinaemia (increased fat droplets in mucosal cells) (12 Dec 1998) |