| signal sequence | A peptide present on proteins that are destined either to be secreted or to be membrane components. It is usually at the N terminus and normally absent from the mature protein. Normally refers to the sequence (ca 20 amino acids) that interacts with signal recognition particle and directs the ribosome to the endoplasmic reticulum where co translational insertion takes place. Could also refer to sequences that direct post translational uptake by organelles. Signal peptides are highly hydrophobic but with some positively charged residues. The signal sequence is normally removed from the growing peptide chain by signal peptidase, a specific protease located on the cisternal face of the endoplasmic reticulum. See: signal recognition particle. (18 Nov 1997) |
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| signal transduction | The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors. (18 Nov 1997) |
| signal void | In magnetic resonance imaging, a region emitting no radiofrequency signal, either because there are no activated protons in the region (such as flowing blood) or because a different element predominates, particularly calcium. (05 Mar 2000) |
| signal-to-noise ratio | <microscopy> Also sometimes used as an abbreviation for serial number, can be somewhat confusing in the case of electronic equipment. (05 Aug 1998) |
| signate | <zoology> Having definite colour markings. Origin: L. Signatus, p. P. See Sign. Source: Websters Dictionary (01 Mar 1998) |
| signature | 1. A sign, stamp, or mark impressed, as by a seal. "The brain, being well furnished with various traces, signatures, and images." (I. Watts) "The natural and indelible signature of God, which human souls . . . Are supposed to be stamped with." (Bentley) 2. Especially, the name of any person, written with his own hand, employed to signify that the writing which precedes accords with his wishes or intentions; a sign manual; an autograph. 3. <physiology> An outward mark by which internal characteristics were supposed to be indicated. "Some plants bear a very evident signature of their nature and use." (Dr. H. More) 4. <medicine> A resemblance between the external characters of a disease and those of some physical agent, for instance, that existing between the red skin of scarlet fever and a red cloth; supposed to indicate this agent in the treatment of the disease. 5. The designation of the key (when not C major, or its relative, A minor) by means of one or more sharps or flats at the beginning of the staff, immediately after the clef, affecting all notes of the same letter throughout the piece or movement. Each minor key has the same signature as its relative major. 6. A letter or figure placed at the bottom of the first page of each sheet of a book or pamphlet, as a direction to the binder in arranging and folding the sheets. The printed sheet so marked, or the form from which it is printed; as, to reprint one or more signatures. Star signatures (as A, 1) are the same characters, with the addition of asterisks, used on the first pages of offcuts, as in 12mo sheets. 7. <pharmacology> That part of a prescription which contains the directions to the patient. It is usually prefaced by S or Sig. (an abbreviation for the Latin signa, imperative of signare to sign or mark). Origin: F. (cf. It. Signatura, segnatura, Sp. & LL. Signatura), from L. Signare, signatum. See Sign. Source: Websters Dictionary (01 Mar 1998) |
| signature sequence | Short oligonucleotides of unique sequence found in 16S ribosomal RNA of a particular group of prokaryotes. (09 Oct 1997) |
| signet ring | The early stage of trophozoite development of the malaria parasite in the red blood cell; the parasite cytoplasm stains blue around its circular margin, and the nucleus stains red in Romanowsky stains, while the central vacuole is clear, giving the ringlike appearance. (05 Mar 2000) |
| signet ring cells | Altered basophilic cells of the anterior lobe of the pituitary that develop following castration; the body of the cell is occupied by a large vacuole that displaces the nucleus to the periphery, giving the cell a resemblance to a signet ring. Synonym: signet ring cells. (05 Mar 2000) |
| signet-ring cell carcinoma | <tumour> A poorly differentiated adenocarcinoma composed of cells with a cytoplasmic droplet of mucus that compresses the nucleus to one side along the cell membrane; arises most frequently in the stomach, occasionally in the large bowel or elsewhere. (05 Mar 2000) |
| significance | An analytical evaluation of the results of a comparative trial or survey. Data yielding a difference in outcome depending on treatment or environmental factors are considered statistically significant if various mathematical procedures indicate there is less than a one in twenty (five percent) chance that the same results would occur through random accident. (In statistical terms this is expressed as p<.05 -or, the p-value is less than0.05.) (09 Oct 1997) |
| significant | In statistics, probably resulting from something other than chance. (18 Nov 1997) |
| significative | 1. Betokening or representing by an external sign. "The holy symbols or signs are not barely significative." (Brerewood) 2. Having signification or meaning; expressive of a meaning or purpose; significant. "Neither in the degrees of kindred they were destitute of significative words." (Camden) Signif"icatively, Signif"icativeness. Origin: L. Significativus: cf. F. Significatif. Source: Websters Dictionary (01 Mar 1998) |
| Signorelli's sign | <clinical sign> Tenderness on pressure in the glenoid fossa in front of the mastoid process in meningitis. (05 Mar 2000) |
| Signorelli, Angelo | <person> Italian physician, 1876-1952. See: Signorelli's sign. (05 Mar 2000) |
| signing |
sign language: language expressed by visible hand gestures
출처: wordnet.princeton.edu/perl/webwn
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| signal-to-noise ratio |
the ratio of signal intensity to noise intensity
출처: wordnet.princeton.edu/perl/webwn
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| signet ring |
a ring bearing a signet
출처: wordnet.princeton.edu/perl/webwn
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| sigma virus |
a congenitally transmitted genus of rhabdoviruses that induces carbon dioxide sensitivity in Drosophila melanogaster and other fruit flies.
출처: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| sigmoid cystoplasty |
cystoplasty in which a portion of the sigmoid colon is used to reconstruct or augment the bladder.
출처: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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| SIG | a character indicating a relation between quantities |
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| SIG | a gesture that is part of a sign language |
| SIG | (linguistics) a fundamental linguistic unit linking a signifier to that which is signified |
| SIG | an event that is experienced as indicating important things to come |
| SIG | (astrology) one of 12 equal areas into which the zodiac is divided |
| SIG | having an indicated pole (as the distinction between positive and negative electric charges) |
| SIG | (medical) any objective evidence of the presence of a disorder or disease |
| SIG | make the sign of the cross over someone in order to call on God for protection |
| SIG | be engaged by a written agreement |
| SIG | communicate in sign language |
| SIG | mark with one's signature |
| SIG | communicate silently and non-verbally by signals or signs |